Publications by authors named "Jason A Parnes"

Article Synopsis
  • The study aimed to evaluate surgeons' understanding of the costs associated with disposable surgical instruments and consumables, and to assess interest in more cost information.
  • A survey conducted at McGill University and Western University revealed that surgeons' estimations of product costs were largely inaccurate, with an average accuracy rate of only 29.9%.
  • The majority of participants (82%) expressed that having better access to cost information could influence their purchasing decisions regarding consumables.
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Background: Inflammatory bowel diseases, encompassing Crohn's disease and ulcerative colitis, are characterised by persistent leucocyte tissue infiltration leading to perpetuation of an inappropriate inflammatory cascade. The neuronal guidance molecule netrin-1 has recently been implicated in the orchestration of leucocyte trafficking during acute inflammation. We therefore hypothesised that netrin-1 could modulate leucocyte infiltration and disease activity in a model of inflammatory bowel disease.

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The relative contribution to brain cholinergic signaling by synaptic- and diffusion-based mechanisms remains to be elucidated. In this study, we examined the prevalence of fast nicotinic signaling in the hippocampus. We describe a mouse model where cholinergic axons are labeled with the tauGFP fusion protein driven by the choline acetyltransferase promoter.

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