Publications by authors named "Jasna Cotic"
Objectives: Autoreactive memory B cells (MBCs) contribute to chronic and progressive courses in autoimmune diseases like SLE. The efficacy of belimumab (BEL), the first approved biologic treatment for SLE and LN, is generally attributed to depletion of activated naïve B cells and inhibition of B-cell activation. BEL's effect on MBCs is currently unexplained.
View Article and Find Full Text PDFObjective: 3Y-TZP ceramics with reduced alumina content have improved translucency and are used in monolithic dental restorations without porcelain-based veneers. The workflow can be further streamlined with rapid sintering. This study was designed to assess how these approaches affect ageing when the materials are exposed to the oral environment in vivo.
View Article and Find Full Text PDFObjective: In vivo aging of biomedical grade 3Y-TZP ceramics in the oral environment was assessed and compared to artificially accelerated in vitro hydrothermal aging extrapolations at 37°C.
Methods: 88 discs were pressed and sintered (1450-1500°C) from two commercial 3Y-TZP compositions containing 0.25% AlO to generate finer- and coarser-grained specimens.
Objective: The combined effects of alumina airborne-particle abrasion and prolonged in vitro ageing on the flexural strength of 3Y-TZP ceramic have been studied. The aim was to identify the different effects on the surface and subsurface regions that govern the performance of this popular bioceramic known for its susceptibility to low-temperature degradation (LTD).
Methods: As-sintered or airborne-particle abraded 3Y-TZP discs were subjected to ageing at 134°C for up to 480h.
Background: Slovenia has a high burden of head and neck cancer. Patients are mostly treated with surgery followed by radiation therapy. Advanced surgical and prosthodontic techniques have expanded the rehabilitation options.
View Article and Find Full Text PDFObjectives: This study was designed to explore the complex relationships between the sintering-temperature-dependent grain size, airborne-particle abrasion, ageing and strength of 3Y-TZP ceramics.
Methods: Biomedical grade 3Y-TZP powder was used to fabricate 180 discs. Half of them were sintered at 1400°C for 2h and half at 1500°C for 2h.
Objectives: To evaluate oral health status of the elderly, living in eight randomly selected residential homes for senior citizens across the country.
Background: The percentage of the elderly is growing worldwide. With ageing, risks of various oral diseases, including dental caries and periodontal disease, are growing.