Optical pH measurement system using a single fluorescent dye for assessing susceptibility to dental caries (Erratum).

The erratum corrects a grant number listed in Acknowledgments section of the original article.

A variable resolution approach for improved acquisition of hyperpolarized C metabolic MRI.

Purpose: To ameliorate tradeoffs between a fixed spatial resolution and signal-to-noise ratio (SNR) for hyperpolarized C MRI.

Methods: In MRI, SNR is proportional to voxel volume but retrospective downsampling or voxel averaging only improves SNR by the square root of voxel size. This can be exploited with a metabolite-selective imaging approach that independently encodes each compound, yielding high-resolution images for the injected substrate and coarser resolution images for downstream metabolites, while maintaining adequate SNR for each.

Optical pH measurement system using a single fluorescent dye for assessing susceptibility to dental caries.

Sugar-rich diets and poor dental hygiene promote the formation of a biofilm (plaque) that strongly adheres to the dental enamel surface and fosters the evolution of aciduric bacteria. The acid contributes to demineralization of the exterior tooth enamel, which accelerates after the pH drops below a critical value (∼5.5) for extended time periods resulting in the need for restorative procedures.

Dental pH Opti-Wand (DpOW): measuring oral acidity to guide enamel preservation.

Undetected caries can lead to painful cavities and surgical restorations. Lack of proper detection tools makes caries prevention dependent on dentist's expertise and presents obstacles in oral health monitoring. To overcome this problem, we have developed a new approach to predict early stages of enamel demineralization caused by oral bacteria.

Driving After Adolescent Concussion: Advice From Nurse Practitioners in the Absence of Standardized Recommendations.

Introduction: Nurse practitioners (NPs) are authorized to manage concussion recovery. Common adolescent activities, like driving, are omitted from guidelines. We investigated NP driving guidance and its clinical basis for restriction or limitation following adolescent concussion.