Publications by authors named "Jasmine Rah"
Article Synopsis
- During the early months of the COVID-19 pandemic, the risks of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pregnant women were unclear, highlighting the need for research on infection rates in this population.
- The study aimed to estimate SARS-CoV-2 infection rates among pregnant women in Washington State and assess disparities based on race, ethnicity, and English language proficiency.
- Researchers identified 240 pregnant patients with confirmed SARS-CoV-2 infections, with over 70% belonging to minority racial and ethnic groups, indicating notable disparities in infection rates.
Disease severity, pregnancy outcomes, and maternal deaths among pregnant patients with severe acute respiratory syndrome coronavirus 2 infection in Washington State.
Am J Obstet Gynecol
July 2021
Article Synopsis
- Pregnant patients with COVID-19 in Washington State showed increased risks of severe disease, hospitalization, and mortality, with 1 in 11 developing severe illness and 1 in 80 dying during the study period.
- Hospitalization rates for pregnant patients were significantly higher, at 10%, compared to 2.8% for similarly aged adults, indicating a 3.5-fold increase in risk.
- Those hospitalized were more likely to have underlying health conditions, such as asthma, hypertension, and obesity, revealing a link between pre-existing morbidities and severe COVID-19 outcomes in pregnancy.
Objective: Type B aortic dissection (TBAD) is commonly thought of as a sporadic event. However, an increasing body of data has suggested that genetic factors can influence TBAD. Our aim was to determine the prevalence of heritable TBAD, defined as either syndromic TBAD or nonsyndromic familial TBAD and to detail the natural history and long-term clinical outcomes compared with patients with "sporadic" TBAD without an identified syndrome or family history.
View Article and Find Full Text PDFBackground: The impact of coronavirus disease 2019 on pregnant women is incompletely understood, but early data from case series suggest a variable course of illness from asymptomatic or mild disease to maternal death. It is unclear whether pregnant women manifest enhanced disease similar to influenza viral infection or whether specific risk factors might predispose to severe disease.
Objective: To describe maternal disease and obstetrical outcomes associated with coronavirus disease 2019 in pregnancy to rapidly inform clinical care.
Alveolar macrophages orchestrate pulmonary innate immunity and are essential for early immune surveillance and clearance of microorganisms in the airways. Inflammatory signaling must be sufficiently robust to promote host defense but limited enough to prevent excessive tissue injury. Macrophages in the lungs utilize multiple transcriptional and post-transcriptional mechanisms of inflammatory gene expression to delicately balance the elaboration of immune mediators.
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