Severe hypertriglyceridemia in pregnancy, defined as triglycerides >1000 mg/dL, is a rare but high-acuity condition that can precipitate several complications for the mother and fetus, in particular hypertriglyceridemia-induced acute pancreatitis (HTGAP). The treatments employed in the management of hypertriglyceridemia-induced acute pancreatitis (HTGAP) have the potential to significantly alter the anesthetic course of an impending or emergent delivery. In this report, we present two cases of HTGAP, one complicated by a concomitant COVID-19 infection and each with a unique approach to anesthetic management in the setting of two very different and cofounded clinical presentations.
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