Publications by authors named "Jasmine Messina"
Clin Chim Acta
September 2021
Article Synopsis
- Pseudohyponatremia is an artifact causing falsely low plasma sodium levels in samples with high proteins or lipids, influenced by inappropriate cutoffs for lipemia detection.
- Researchers tested two methods to establish a more accurate lipemic cutoff for sodium: one using spiked plasma samples with Intralipid®, and another using naturally hyperlipidemic samples measured by direct methods.
- Results showed that Intralipid® did not mimic the lipemic interference seen in pseudohyponatremia, with significant sodium deviations occurring in samples with an L-index above 700, prompting a recommendation for lower lipemia tolerance in clinical labs.
