Publications by authors named "Jasmine Mann"

Article Synopsis
  • Checkpoint inhibitors (CPI) have significantly improved survival rates for various cancers but can lead to rare autoimmune blistering disorders, such as bullous pemphigoid (BP).
  • A study reviewed bullous skin-related immune adverse events associated with CPI therapy in over 7,300 patients, finding that BP occurred in 0.3% of cases, predominantly affecting older males with cutaneous melanoma.
  • Most patients experienced symptoms within 12 months of treatment, and management often required multiple lines of therapy, with a considerable number of patients needing to discontinue or pause CPI treatments due to skin toxicity.
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Mohs micrographic surgery (MMS) is a precise and effective method commonly used to treat high-risk basal cell carcinoma and squamous cell carcinoma on the head and neck. Although the majority of evidence for MMS relates to keratinocyte cancers, there is published evidence for other types of skin cancer. This review aims to discuss the evidence for using MMS to treat six different types of skin cancer [malignant melanoma, lentigo maligna, dermatofibrosarcoma protuberans, atypical fibroxanthoma (AFX), microcystic adnexal carcinoma and pleomorphic dermal sarcoma (PDS)] particularly in the context of survival rates and cancer recurrence.

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Understanding patient concerns regarding skin surgery during the COVID-19 pandemic is a vital way of learning from individual experiences. A shift towards using superficial absorbable sutures (AS) has been anecdotally observed. We explored patient attitudes to the use of AS, and their experiences and perceptions of attending for skin surgery during the pandemic.

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Purpose: The immune checkpoint inhibitors (ICIs) have resulted in subgroups of patients with metastatic melanoma achieving high-quality durable responses. Metastatic melanoma survivors are a new population in the era of cancer survivorship. The aim of this study was to evaluate metastatic melanoma survivors in terms of health-related quality of life (HRQoL), immune-related adverse events (irAEs) and exposure to immunosuppressive agents in a large single centre in the UK.

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