Effect of sertraline and fluvoxamine on quality of life in patients with obsessive-compulsive disorder: A 12-week interventional study.

Background: Obsessive-compulsive disorder (OCD) is associated with poor quality of life (QoL) and functionality. Treatment leads to improvement in QoL and better functioning.

Aim: To assess the effect of treatment with SSRIs on QoL and disability in first-episode, drug-naïve patients with OCD.

A randomized, open-label pilot trial of selective serotonin reuptake inhibitors on neuropsychological functions in patients with obsessive compulsive disorder.

Background: There is enough empirical literature suggesting impairments in neuropsychological functioning in patients with obsessive compulsive disorder (OCD) despite inconsistencies.

Aim: The aim of the index study was to study the effect of Selective Serotonin Reuptake Inhibitors (SSRIs) on neuropsychological functions and illness severity in drug-naïve subjects with OCD.

Methods: A total of 50 subjects with diagnosis of obsessive-compulsive disorder (DSM-5) in the age range of 18-55 years, drug naïve, without comorbid depression/anxiety disorders were randomized to receive either Sertraline or Fluvoxamine.

Early Improvement as a Predictor of Treatment Response in Patients With Obsessive-Compulsive Disorder: A 12-Week Randomized Trial of Sertraline and Fluvoxamine.

Early response to selective serotonin reuptake inhibitors (SSRIs) at 4 weeks may predict response at 12 weeks. The objective of this study was to examine if early response to SSRIs can reliably indicate future response to the same drug, while simultaneously comparing 2 medications frequently used to treat obsessive-compulsive disorder (OCD): sertraline and fluvoxamine. This was a randomized, open-label prospective study of 50 drug-naive patients with OCD (per criteria) conducted from January 2019 to November 2020 in the outpatient department of a tertiary care teaching hospital in North India.

In vitro seed germination of economically important edible bamboo Dendrocalamus membranaceus Munro.

An in vitro propagation protocol using mature seeds of D. membranaceus was successfully established. Scarcity of seeds in bamboos because of their long flowering periods and irregular seed set resulting in low viability and germination potential, motivated us to undertake the present study.