Publications by authors named "Jaslin Orelus"

Article Synopsis
  • Hepatorenal syndrome (HRS) is a serious condition linked to advanced liver disease, characterized by a rapid decline in kidney function, with high mortality rates despite recent treatment advancements.
  • A meta-analysis of 29 studies, selected from over 8,000, showed that vasoconstrictor agents like terlipressin can improve kidney function and reduce the need for dialysis but do not significantly lower mortality rates.
  • The findings suggest that while vasoconstrictors are beneficial for managing HRS, there is a clear need for personalized treatment plans and further research to identify more effective therapies that improve survival outcomes without increasing side effects.
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Endoscopic cholangiopancreatography (ERCP) is a widely used diagnostic and therapeutic tool for pancreaticobiliary conditions. One of its major complications is pancreatitis. This study aims to understand the incidence of post-ERCP pancreatitis after using rectal diclofenac and Indomethacin as prophylactic measures.

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Autoimmune thyroid diseases (AITDs) pose significant challenges in clinical practice, representing one of the most common endocrine abnormalities. Vitamin D deficiency has been linked as one of the contributing factors to the etiology of AITDs. This systematic review evaluates the effects of vitamin D supplementation on thyroid-stimulating hormone (TSH), triiodothyronine (T3), and thyroxine (T4) levels in adults with AITDs.

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Migraine causes debilitating headaches and significantly impacts quality of life. Effective migraine-specific treatments have been lacking until the advent of monoclonal antibodies (mAbs) targeting calcitonin gene-related peptide (CGRP) receptors, which have expanded therapy options for migraine treatment. This study explores the short- and long-term efficacy and safety of erenumab in migraine treatment.

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