Publications by authors named "Jasen Kundalic"
Background And Aims: Vitamin D receptor (VDR) genetic variants are considered to have a role in the pathogenesis of rheumatoid arthritis (RA). This study examines an association of FokI, BsmI, ApaI and TaqI with RA, as well as with bone mineral density (RA with normal bone mineral density, RA-NBMD; RA with associated osteopenia, RA-OSTP; and RA with associated osteoporosis, RA-OP) and inflammatory markers.
Materials And Methods: VDR genetic variants were tested in 248 subjects using the PCR-RFLP method.
Article Synopsis
- Diabetic neuropathy is a common complication of diabetes, influenced by long-term metabolic and vascular factors affecting different nerve layers.
- The study involved 15 sural nerve samples divided into diabetic, peripheral vascular disease, and control groups, revealing significant structural changes in diabetic nerves, such as increased perineurial and endoneurial connective tissue.
- These findings suggest that hyperglycemia and ischemia in diabetes contribute to thickening and fibrosis in nerve sheaths, which may hinder nerve regeneration and homeostasis, prompting further research into the extracellular matrix in diabetic nerves.