Superficial femoral artery aneurysms: an unusual entity?

Objective: The purpose of this study was to investigate the mode of presentation of superficial femoral artery aneurysms, their association with other arterial aneurysms, and their operative treatment.

Method: Records of patients with superficial femoral artery aneurysms seen at our institution from 1990 to 2000 were reviewed retrospectively with attention to presenting symptoms, clinical examination, arteriographic findings, and operative management.

Results: Eleven of 13 aneurysms (85%) were in men.

Progression of asymptomatic carotid stenosis: a natural history study in 1004 patients.

Purpose: The purpose of this study was to delineate the natural history of the progression of asymptomatic carotid stenosis.

Methods: In a 10-year period, 1701 carotid arteries in 1004 patients who were asymptomatic were studied with serial duplex scans (mean follow-up period, 28 months; mean number of scans, 2.9/patient).

Long-term results of femoropopliteal bypass with stabilized human umbilical vein.

Background: Stabilized human umbilical vein (SHUV) is one of several graft materials that may be used when autogenous saphenous vein is absent or inadequate, or when a shortened anesthesia time is deemed necessary.

Methods: Two hundred eleven consecutive femoropopliteal bypasses were used in 171 patients since 1977. Follow-up has been conducted at regular intervals since operation, and the results scrutinized according to operative indication, diabetic status, and the number of runoff vessels.

Cavernous hemangioma of the cephalic vein.

Although capillary and venous hemangiomas are common problems in children, cavernous hemangiomas of extremity veins in adults are unusual. Successful operative removal of a cavernous hemangioma in the right forearm of a 37-year-old man is described. To the author's knowledge, such lesions in named upper-extremity veins have not previously been reported.

Anastomotic suture materials and experimental colorectal carcinogenesis.

Local tumor recurrence following restorative surgery for colorectal cancer may occasionally result from the promotion of a neoplastic lesion in a zone of proliferative instability adjacent to the anastomosis. The aim of this study was to compare the influence of three anastomotic suture materials, including stainless steel (as a model of surgical stapling), on colorectal carcinogenesis in an experimental animal model. The transmural implantation of stainless steel sutures into the distal descending colon of albino Swiss rats during the postinitiation phase of tumor induction resulted in significantly fewer animals exhibiting perianastomotic tumors 12 weeks later (3 of 21 animals) when compared with either polyamide (Nurolon; Ethicon, Edinburgh, United Kingdom) (14 of 20 animals; P less than 0.

Reoperation for complications of stabilized human umbilical vein grafts.

Among 211 femoropopliteal bypass grafts constructed with stabilized human umbilical vein performed between 1977 and 1986, 3 major complications were seen: graft thrombosis, aneurysm formation, and infection. Early thrombosis (within 30 days of operation) was successfully treated in 14 of 17 patients (82 percent) with either graft thrombectomy (13 of 17 patients) or graft replacement (1 patient). Late graft closure (2 to 55 months after operation) was successfully treated with thrombectomy in 17 of 28 patients (61 percent) or graft revision or replacement in 4 patients (14 percent).

Inflammatory aneurysms of the abdominal aorta.

Inflammatory aneurysms of the abdominal aorta (IAAAs) have distinctive clinical and physical characteristics that separate them from typical atherosclerotic aneurysms. They were identified in 19 (7.2%) of 265 patients undergoing abdominal aortic aneurysm repair.

Dietary manipulation during experimental colorectal carcinogenesis: a morphological study in the rat.

The effect of the dietary manipulation of fat and fibre on the gross pathological, histopathological and scanning electron microscopic appearances of colonic mucosa was studied before and during experimental carcinogenesis in 232 male Albino Swiss rats. Carcinogen treated animals were given 12 consecutive weekly injections of Azoxymethane in a dose of 10 mg/kg per week. The animals were divided between four dietary groups (1: high fat high fibre, 2: low fat high fibre, 3: high fat low fibre and 4: low fat low fibre).

Morphological and cell kinetic effects of dietary manipulation during colorectal carcinogenesis.

The effect of dietary manipulation of fat and fibre on the structural and cell kinetic characteristics of colonic mucosa was studied before and during experimental carcinogenesis in 232 male Albino Swiss rats. Carcinogen treated animals were given 12 weekly injections of azoxymethane (10 mg/kg/week). The animals were divided between four dietary groups (1) high fat, high fibre, (2) low fat, high fibre, (3) high fat, low fibre and (4) low fat, low fibre.

Experimental colorectal cancer: the relationship of diet and faecal bile acid concentration to tumour induction.

Epidemiological studies have consistently suggested an aetiological relationship between certain dietary constituents, faecal bile acid (FBA) concentration and colorectal cancer. This study was designed to examine the effect of the dietary manipulation of fat and fibre on tumour induction and on various faecal characteristics in Albino Swiss rats. A total of 232 animals were maintained on one of four different diets for 4, 20 and 28 weeks respectively.

Small-bowel obstruction caused by intraluminal migration of prosthetic grafts.

Two patients who had undergone prosthetic grafting in the venous system presented with small-bowel obstruction. The first had undergone mesocaval shunting with a Dacron graft and the second, replacement of the inferior vena cava with a polytetrafluoroethylene graft after an extensive resection of retroperitoneal tumor. In both instances the grafts were within the lumen of the small bowel, causing a mechanical obstruction.

Colorectal cancer in young adults.

This retrospective study reviews our experience of the management of colorectal cancer in 481 consecutive patients. Details of presentation, surgery, Dukes staging, histological grading, recurrence and survival were analysed. We have compared patients 50 years of age and over with their younger counterparts.

The use of stabilized human umbilical vein for femoropopliteal bypass. Experience with 133 operations with 5-year follow-up.

One hundred thirty-three femoropopliteal bypasses using stabilized human umbilical vein were performed in 116 patients during a 5-year period. The indications for operation were claudication in 35% and limb salvage in 65%. There were eight deaths in the postoperative period, all due to myocardial infarctions, and all occurring in patients operated upon for limb salvage.

Colon and rectal carcinoma in the west of Scotland. Symptoms, histologic characteristics, and outcome.

Multiple clinical and pathologic factors have been analyzed retrospectively for a group of 456 patients with colon and rectal cancer treated in Glasgow over a span of 4 years. Sixty-five percent of these patients underwent curative resection, and another 16 percent had palliative resection. Obstruction and perforation (present in 19 and 5 percent, respectively) were associated with the highest operative mortality (17 percent for both) of any presenting symptom.

Modulation of human peripheral blood lymphocyte Fc gamma receptors by immune complexes: recovery of Fc gamma receptors in the presence of normal human serum.

When normal human peripheral blood lymphocytes (PBL) were incubated at 37 degrees with soluble transferrin anti-transferrin (TAT) complexes a significant reduction in the proportion of PBL bearing receptors for the reacted Fc portion of IgG(Fc gamma R) was found. Following incubation of such complex-treated PBL in normal human serum the proportion of Fc gamma R + PBL, as assessed by rosette formation with chicken erythrocytes (E) presensitized with rabbit antibody (A) was found to be significantly increased. Such serum-mediated recovery of Fc gamma R was not affected by pretreating PBL with cycloheximide.

Current diagnosis and management of upper extremity ischemia.

Although the causes of upper extremity ischemia are diverse, their management follows well established surgical principles in most instances. Evaluation that emphasizes precise physical examination and exploits simple noninvasive determinations aids in reducing cost and complexity. Subclavian occlusive lesions are optimally managed by bypass procedures that avoid thoracotomy.