Comparison of microencapsulation properties of spruce galactoglucomannans and arabic gum using a model hydrophobic core compound.

In the present study, microencapsulation and the physical properties of spruce ( Picea abies ) Omicron-acetyl-galactoglucomannans (GGM) were investigated and compared to those of arabic gum (AG). Microcapsules were obtained by freeze-drying oil-in-water emulsions containing 10 wt % capsule materials (AG, GGM, or a 1:1 mixture of GGM-AG) and 2 wt % alpha-tocopherol (a model hydrophobic core compound that oxidizes easily). Microcapsules were stored at relative humidity (RH) of 0, 33, and 66% at 25 degrees C for different time periods, and their alpha-tocopherol content was determined by HPLC.

Investigations on the humidity-induced transformations of salbutamol sulphate particles coated with L-leucine.

Purpose: The crystallization and structural integrity of micron-sized inhalable salbutamol sulphate particles coated with L-leucine by different methods are investigated at different humidities. The influence of the L-leucine coating on the crystallization of salbutamol sulphate beneath the coating layer is explored.

Methods: The coated particles are prepared by an aerosol flow reactor method, the formation of the L-leucine coating being controlled by the saturation conditions of the L-leucine.

Synthesis and characterisation of cyclopentadienyl complexes of barium: precursors for atomic layer deposition of BaTiO3.

Cyclopentadienyl complexes Ba(C5Me5)2(THF)2 (1), Ba(C5Me5)2(A) (A = THF, dien, trien, diglyme, triglyme) (2-5), Ba(Pr(i)3C5H2)2(THF)2 (6), Ba(Bu(t)3C5H2)2(THF) (7), Ba(Me2NC2H4C5Me4)2 (8) and Ba(EtOC2H4C5Me4)2 (9) were prepared and characterised with TGA/SDTA, NMR and MS. Crystal structures of 2, 4, 5, 7, 8 and 9 are presented. All complexes prepared sublime under reduced pressure and complexes 1, 6 and 7 showed volatility also under atmospheric pressure.

Polymeric drug nanoparticles prepared by an aerosol flow reactor method.

Purpose: Our purpose was to study the possibility of using a novel method, namely, aerosol flow reactor method, for the preparation of drug-containing nanoparticles with varying amounts of drug and polymer. The physical properties of the prepared nanoparticles were analyzed.

Methods: The nanoparticle size distributions were measured using differential mobility analyzer.

An anthracene dimer with a fused 1,3-dithiole ring at 193 K.

The first butterfly-shaped anthracene dimer including S atoms,8,9-dihydro-3a,8[1',2']:9,13b[1",2"]dibenzenodibenzo[3,4:7,8]cycloocta[1,2-d]-1,3-dithiole, C29H20S2, contains an exceptionally long Csp3-Csp3 bond of 1.672 (2) A in the fused 1,3-dithiole ring. The length of the other bond bridging the anthracene moieties is 1.