Effectiveness of oral zinc supplementation in the treatment of idiopathic sudden sensorineural hearing loss (ISSNHL).

Objective: Investigate the benefit of zinc supplement combined with standard treatment ofidiopathic sudden sensorineural hearing loss (ISSNHL) patients.

Material And Method: A prospective, randomized study was designed to evaluate the hearing outcomes in ISSNHL patients treated with zinc supplement. The patients were randomized into two groups, the study and the control group.

Minimally invasive palatal surgery for obstructive sleep apnea.

Obstructive sleep apnea (OSA) is a common condition in Thai population characterized by recurrent episodes of apnea during sleep. Patients may have detrimental consequences and the management of OSA is complex and challenging. Many patients respond to medical treatments including weight loss, body position training, oral appliances and continuous positive airway pressure (CPAP).

Patterns of anomalies of structures of the middle ear and the facial nerve as revealed in newborn temporal bones.

Hypothesis: The purpose of this study is to offer new data about facial nerve malformations in the tympanic cavity.

Background: Prospective anatomic study of newborns to demonstrate the submacroscopic anatomy of the intratympanic facial nerve and its surrounding structures by malformations.

Methods: Step-by-step microdissection of 12 newborn temporal bones and histologic evaluation of 4 middle ears showing multiple malformations.

Nanoparticle size is a critical physicochemical determinant of the human blood plasma corona: a comprehensive quantitative proteomic analysis.

In biological fluids, proteins associate with nanoparticles, leading to a protein "corona" defining the biological identity of the particle. However, a comprehensive knowledge of particle-guided protein fingerprints and their dependence on nanomaterial properties is incomplete. We studied the long-lived ("hard") blood plasma derived corona on monodispersed amorphous silica nanoparticles differing in size (20, 30, and 100 nm).