We examine the role of big data and machine learning in cancer research. We describe an example in cancer research where gene-level data from The Cancer Genome Atlas (TCGA) consortium is interpreted using a pathway-level model. As the complexity of computational models increases, their sample requirements grow exponentially.
View Article and Find Full Text PDFPurpose: A large share of the information in electronic medical records (EMRs) consists of free-text compositions. From a computational point-of-view, the continuing prevalence of free-text entry is a major hindrance when the goal is to increase automation in EMRs. However, the efforts in developing standards for the structured representation of medical information have not proven to be a panacea.
View Article and Find Full Text PDFIEEE Trans Inf Technol Biomed
November 2008
An approach coined as "reflective information management" is presented as a technique for the management of emergency department chief complaint information. The architecture of a system integrating principles from this approach is described and its performance is evaluated in providing categorical information from free-text chief complaints for use, e.g.
View Article and Find Full Text PDFBiomed Inform Insights
July 2016
The goal of this study is to present the experiences gathered from the migration of an existing and deployed joint replacement surgery information system from a classical 2-tier architecture to a 4-tier architecture. These include discussion on the motivation for the migration and on the technical benefits of the chosen technical migration path and an evaluation of user experiences. The results from the analysis of clinical end-user and administrator experiences show an increase in the perceived performance and maintainability of the system and a high level of acceptance for the new system version.
View Article and Find Full Text PDFScand J Prim Health Care
March 2006
Objective: To evaluate the impact of the reorganization of oral AC treatment management in a primary healthcare setting in terms of quality of care and cost of care. The evaluated reorganization involved the adoption of an AC nurse service model supported by the use of information and communication technology for storing and handling follow-up data.
Design: Statistical analysis of AC follow-up data, personnel task distribution and resource use analysis, and survey of personnel experiences.
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