Publications by authors named "Jared Rispens"

Article Synopsis
  • The study investigates the presence of SARS-CoV-2 on surfaces in households with confirmed COVID-19 cases, highlighting the potential for transmission through fomites.
  • It involved sampling 15 surfaces in 10 households, finding SARS-CoV-2 RNA in 15% of the samples, predominantly on nightstands, pillows, and light switches.
  • Although viable virus was detected from one sample, the findings suggest that while surface contamination can occur, the risk of transmission through surfaces is relatively low, particularly early in the infection.
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In October 2018, the Centers for Disease Control and Prevention was notified of a cluster of Legionnaires' disease cases in workers at a racetrack facility. The objective of the resulting investigation was to determine the extent of the outbreak and identify potential sources of exposure to halt transmission. Case-finding and interviews were conducted among symptomatic racetrack workers who were known to be at the facility within 14 days prior to symptom onset.

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Virus shedding in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can occur before onset of symptoms; less is known about symptom progression or infectiousness associated with initiation of viral shedding. We investigated household transmission in 5 households with daily specimen collection for 5 consecutive days starting a median of 4 days after symptom onset in index patients. Seven contacts across 2 households implementing no precautionary measures were infected.

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Article Synopsis
  • The study explored how SARS-CoV-2 spreads within households in the U.S. and calculated the household secondary infection rate (SIR) to help develop strategies for reducing transmission.
  • Researchers recruited patients with confirmed SARS-CoV-2 infections and their household members in Utah and Wisconsin, gathering demographic data and conducting tests over several visits.
  • Results showed a 29% overall secondary infection rate, with higher rates among children and spouses, indicating that individuals with weakened immune systems or diabetes are at greater risk, suggesting the need for strict self-isolation measures.
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Background And Objectives: Limited data exist on severe acute respiratory syndrome coronavirus 2 in children. We described infection rates and symptom profiles among pediatric household contacts of individuals with coronavirus disease 2019.

Methods: We enrolled individuals with coronavirus disease 2019 and their household contacts, assessed daily symptoms prospectively for 14 days, and obtained specimens for severe acute respiratory syndrome coronavirus 2 real-time reverse transcription polymerase chain reaction and serology testing.

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Background: Extended-spectrum β-lactamase (ESBL)-producing Enterobacterales-(Ent) infections are increasing in pediatrics. Before CTX-M ESBL emerged, the most common infection-associated ESBL genes were TEM and SHV-type ESBLs. We sought to define the current epidemiology of Ent infections in children due to blaTEM and blaSHV (TEM-SHV-Ent).

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Article Synopsis
  • The study analyzed mild and asymptomatic cases of SARS-CoV-2 by observing 198 household contacts in Wisconsin and Utah during a 14-day period.
  • Results showed that common symptoms upon positive COVID-19 testing included upper respiratory (68%) and neurological symptoms (64%), while fever was less commonly reported (19%).
  • A notable 17% of participants were asymptomatic at the time of testing, but all eventually developed symptoms, highlighting the need for effective infection control and contact tracing measures.
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On April 25, 2019, a farm tractor towing two 2-ton ammonia tanks on a county road in Lake County, Illinois, experienced a mechanical failure that resulted in the release of anhydrous ammonia, a colorless, pungent, irritating gas that can cause severe respiratory and ocular damage (1). Approximately 80% of anhydrous ammonia produced in the United States is used as a fertilizer in agriculture (1). Eighty-three persons, including first responders, motorists, and neighborhood residents, were evaluated at area hospitals because of exposure to the gas.

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Introduction: The pandemic of extended-spectrum beta-lactamase-(ESBL)-producing Enterobacteriaceae (Ent) is strongly linked to the dissemination of CTX-M-type-ESBL-Ent. We sought to define the epidemiology of infections in children due to an emerging resistance type, CTX-M-9-group-producing-Ent (CTX-M-9-grp-Ent).

Methods: A retrospective matched case-control analysis of children with CTX-M-9-grp-Ent infections who received medical care at three Chicago area hospitals was performed.

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Background: Fluoroquinolones are uncommonly prescribed in children, yet pediatric multidrug resistant (MDR) enterobacteriaceae (Ent) infections often reveal fluoroquinolone resistance (FQR). We sought to define the molecular epidemiology of FQR and MDR-Ent in children.

Methods: A case-control analysis of children with MDR-Ent infections at 3 Chicago hospitals was performed.

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