Publications by Jared Joshua Duran

Publications by authors named "Jared Joshua Duran"

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High baseline perivascular space volume in basal ganglia is associated with attention and executive function decline in Parkinson's disease.

Ryan Patrick Foreman Erin Kaye Donahue Jared Joshua Duran Dawn M Schiehser Andrew Petkus

Brain Behav

July 2024

Article Synopsis

The study investigates how pathologic perivascular spaces (PVS) in the brain relate to cognitive decline in Parkinson's disease (PD), focusing on specific cognitive areas over two years.
Researchers used MRI to measure PVS volume in different brain regions, combined with neuropsychological tests assessing various cognitive functions.
Results indicated that a higher PVS volume in the basal ganglia correlated with significant declines in attention, executive function, and overall cognitive performance in individuals with PD.

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Increased perivascular space volume in white matter and basal ganglia is associated with cognition in Parkinson's Disease.

Erin Kaye Donahue Ryan Patrick Foreman Jared Joshua Duran Michael Walter Jakowec Joseph O'Neill

Brain Imaging Behav

February 2024

Perivascular spaces (PVS), fluid-filled compartments surrounding brain vasculature, are an essential component of the glymphatic system responsible for transport of waste and nutrients. Glymphatic system impairment may underlie cognitive deficits in Parkinson's disease (PD). Studies have focused on the role of basal ganglia PVS with cognition in PD, but the role of white matter PVS is unknown.