Publications by authors named "Jared Francis Stefanick"
Article Synopsis
- Targeted liposomal nanoparticles can effectively deliver drugs to cancer cells, but they often interact with healthy tissue due to shared receptor expression, causing side effects.
- By using a dual-receptor targeting strategy, this approach improves selectivity by binding specifically to multiple tumor cell receptors, which allows for discrimination between cancerous and healthy cells.
- In a study on multiple myeloma, a finely-tuned formulation of dual-targeted liposomes showed a significant increase in uptake by cancer cells, achieving a 28-fold selectivity towards cells expressing both targeted receptors compared to those that do not.
