A Study of Orthopedic Patient Leaflets and Readability of AI-Generated Text in Foot and Ankle Surgery (SOLE-AI).

Introduction The internet age has broadened the horizons of modern medicine, and the ever-increasing scope of artificial intelligence (AI) has made information about healthcare, common pathologies, and available treatment options much more accessible to the wider population. Patient autonomy relies on clear, accurate, and user-friendly information to give informed consent to an intervention. Our paper aims to outline the quality, readability, and accuracy of readily available information produced by AI relating to common foot and ankle procedures.

Recommendations for guidelines for promoting mental health in the workplace: an umbrella review.

Objectives: to summarize the recommendations of guidelines for promoting mental health in the workplace.

Methods: an umbrella review, according to Joanna Briggs Institute and Preferred Reporting Items for Systematic reviews and Meta-Analyses methodological assumptions. Data collection was carried out in January 2021 and updated in July 2023 in the American Psychological Association, Cochrane Library, EMBASE, National Library of Medicine, and Scopus databases.

Development and validity of a mobile application prototype for hospital shift handover.

Objective: To develop and validate a mobile application prototype for nursing shift handover in a hospital inpatient unit.

Methods: A methodological study of technological production, carried out from April 2020 to January 2022, for mobile application construction and validity through the Design Thinking methodology. The study involved the stages of prototype development and validity by experts.

Understanding the Impact COVID-19 Has Had on Traumatic Ankle Fractures in a UK Orthopaedic Department: Should Current Guidelines Be Revised?

Introduction Ankle fractures are common yet debilitating injuries. Surgery is the mainstay treatment for ankle fractures displaying a high suspicion of instability. During the coronavirus disease 2019 (COVID-19) pandemic, conservative management became prominent in patients with ankle fractures.

Hyperkeratotic gastritis in two-toed sloths (Choloepus didactylus) from wildlife rescue.

Xenarthran mammals of the suborder Folivora are arboreal species that feed mainly on leaves and Cecropia spp, an abundant plant in the Brazilian Amazon region, is favoured. The stomach of sloths represents 20-30% of their body weight and is adapted to gastric fermentation of plant material. These anatomical and physiological adaptations can be altered by many factors when confined to captivity, which favours fatal gastric conditions.

Promoting mental health in the workplace: web software development and validation.

Objective: to develop and validate the content and technical aspects of a web software program for promoting mental health in the workplace.

Method: applied methodological study and technological development, carried out in three stages: 1) Umbrella review development; 2) Web software development; 3) Content and technical validation carried out by 14 judges. The data was submitted to descriptive statistical analysis and calculation of the content validity index.

Development of an Apple Snack Enriched with Probiotic : Evaluation of the Refractance Window Drying Process on Cell Viability.

The objective of this study was to develop a dried apple snack enriched with probiotics, evaluate its viability using Refractance Window (RW) drying, and compare it with conventional hot air drying (CD) and freeze-drying (FD). Apple slices were impregnated with and dried at 45 °C using RW and CD and FD. Total polyphenol content (TPC), color (∆E*), texture, and viable cell count were measured, and samples were stored for 28 days at 4 °C.

Fractional calculus as a generalized kinetic model for biochemical methane potential tests.

This study presents a fractional calculus model as a generalized kinetic model for estimating the maximum methane yield and degradation kinetics in biomethane potential (BMP) assays, a key analytical method in anaerobic digestion research and application. The fractional model outperformed common first-order kinetic models by yielding superior data fitting and properly managing substrate heterogeneity. The fractional model showed robust performance in mono-digestion, co-digestion and pre-treatment BMP assays with or without presence of large tailing or sigmoidal patterns in the BMP curve.

Introduction of a New Protocol to Limit the Number of Cancelled Elective Orthopaedic Operations Due to Asymptomatic Bacteriuria.

Background Asymptomatic bacteriuria (ASB) poses a significant diagnostic dilemma for medical professionals. Current hospital screening protocol determines the likelihood of a positive diagnosis of a urinary tract infection (UTI) based on the results of a bedside urinalysis. ASB, defined as a positive urine culture in the absence of symptoms, can contribute to unnecessary cancellations, poor utilisation of theatre time, and delayed patient care.

AI-Generated Information for Vascular Patients: Assessing the Standard of Procedure-Specific Information Provided by the ChatGPT AI-Language Model.

Introduction Ensuring access to high-quality information is paramount to facilitating informed surgical decision-making. The use of the internet to access health-related information is increasing, along with the growing prevalence of AI language models such as ChatGPT. We aim to assess the standard of AI-generated patient-facing information through a qualitative analysis of its readability and quality.

Safety and Immunogenicity of Bivalent RSVpreF Vaccine Coadministered With Seasonal Inactivated Influenza Vaccine in Older Adults.

Background: Respiratory syncytial virus (RSV) and influenza are both typically seasonal diseases, with winter peaks in temperate climates. Coadministration of an RSV vaccine and influenza vaccine could be a benefit, requiring 1 rather than 2 visits to a healthcare provider for individuals receiving both vaccines.

Methods: The primary immunogenicity objective of this phase 3, 1:1 randomized, double-blind, placebo-controlled study in healthy adults aged ≥65 years in Australia was to demonstrate noninferiority of immune responses with coadministration of the stabilized RSV prefusion F protein-based vaccine (RSVpreF) and seasonal inactivated influenza vaccine (SIIV) versus SIIV or RSVpreF administered alone, using a 1.

[An assessment of an orhthogeriatrics unit 5 years after its creation].

On January 1st, 2018, we established an orthogeriatrics (OG) unit for patients aged ≥ 70 years old with hip fracture, based on a purely geriatric management 24-hours post-operation. In this article we discuss the results of the implemented measures (geriatric follow-up with standardized protocols) on mortality after 6 weeks, operative delay, and complications. Among the 607 treated patients, the mortality rate was 6.

Development of a mobile application for emergency shift handovers using the National Early Warning Score.

Objective: To develop and validate a prototype of a mobile application shift handover between nurses in the emergency room using a severity scale.

Method: This is a technological tool carried out at the Universidade Estadual de Maringá using design thinking, divided into four phases: discovering, defining, developing, and delivering. To structure the information, a checklist was used based on the Situation Background Assessment Recommendation, and to categorize patients in terms of severity, the National Early Warning Score was used.

Emplacement of the Argyle diamond deposit into an ancient rift zone triggered by supercontinent breakup.

Argyle is the world's largest source of natural diamonds, yet one of only a few economic deposits hosted in a Paleoproterozoic orogen. The geodynamic triggers responsible for its alkaline ultramafic volcanic host are unknown. Here we show, using U-Pb and (U-Th)/He geochronology of detrital apatite and detrital zircon, and U-Pb dating of hydrothermal titanite, that emplacement of the Argyle lamproite is bracketed between 1311 ± 9 Ma and 1257 ± 15 Ma (2σ), older than previously known.

Effect of CO Laser Microperforation Pretreatment on the Dehydration of Apple Slices during Refractive Window Drying.

This research studied the use of CO LASER microperforation as a pretreatment for the refractive window (RW) drying of apple slices with respect to total polyphenol content (TPC), antioxidant capacity, color Δ, and product stability under accelerated storage. For this purpose, the processing variables assessed were pore size (200-600 µm), pore density (9-25 pores/cm), and drying temperature (70-90 °C). As baseline criteria, a comparison with respect to the control without microperforations and samples subjected to conventional tunnel and lyophilization were also considered.

Efficacy of a 4-Antigen Staphylococcus aureus Vaccine in Spinal Surgery: The STaphylococcus aureus suRgical Inpatient Vaccine Efficacy (STRIVE) Randomized Clinical Trial.

Background: Staphylococcus aureus is a global pathogen that is frequently responsible for healthcare-associated infections, including surgical site infections (SSIs). Current infection prevention and control approaches may be limited, with S. aureus antibiotic resistance remaining problematic.

Post-acute COVID and long-COVID among adults and older adults in the State of Paraná, Brazil: protocol for an ambispective cohort study.

Introduction: Since 2020, the world has been going through a viral pandemic with a high morbidity and mortality rate along with the potential to evolve from an acute infection to post-acute and long-COVID, which is still in the process of elucidation. Diagnostic and prognostic research is essential to understand the complexity of factors and contexts involving the illness's process. This protocol introduces a study strategy to analyse predictors, sequelae, and repercussions of COVID-19 in adults and older adults with different disease severities in the State of Paraná, Brazil.

Under the Weather: The Meteorological Effect on Orthopaedic Trauma in Hertfordshire.

Background Effective and efficient use of operating theatres is essential to the smooth running of a trauma service. The paper aims to understand the effect of meteorological factors on the number of referrals and volume and nature of trauma operating cases within our local area. Methods Trauma data over two seasons were analysed in our database, a digital clinical platform that coordinates all admissions and trauma theatre activity.

Construction and validation of clinical scenarios for training informal caregivers of dependent persons.

Objective: To construct and validate three clinical scenarios for training dependent persons' informal caregivers.

Methods: Methodological study, conducted between January and August 2021, in a municipality in the northwest of the state of Paraná. It was developed in two stages: construction of scenarios; and content validation by experts (n = 12).

Assessment of organizational dynamics in a Psychosocial Care Center from the multidisciplinary team's perspective.

Objectives: to assess organizational dynamics in a Psychosocial Care Center for Alcohol and Drugs from the multidisciplinary team's perspective.

Methods: an evaluative, qualitative study, supported by the Fourth Generation Assessment theoretical-methodological framework. It was carried out in a Psychosocial Care Center for Alcohol and Drugs from September 2019 to March 2020.

A Scoping Review of Interventions for Family Bereavement Care during the COVID-19 Pandemic.

The death of a loved one is a major stressor, and bereaved people are at a higher risk of negative health effects. This risk is higher during the COVID-19 pandemic, which raises the need for understanding existing bereavement support interventions. This scoping review aimed to map and summarize findings from the existing literature regarding bereavement support interventions (i.

A Phase 1/2 Study of a Respiratory Syncytial Virus Prefusion F Vaccine With and Without Adjuvant in Healthy Older Adults.

Background: Respiratory syncytial virus (RSV) is an important cause of disease in older adults. We evaluated the safety and immunogenicity of a stabilized RSV prefusion F subunit (RSVpreF) vaccine candidate with/without adjuvant in adults aged 65-85 years.

Methods: Primary cohort participants were equally randomized to 1 of 7 RSVpreF formulations: 60 µg with either Al(OH)3 or CpG/Al(OH)3, 120 µg with either Al(OH)3 or CpG/Al(OH)3, 240 µg with either Al(OH)3 or CpG/Al(OH)3, 240 µg unadjuvanted, or placebo, administered concomitantly with high-dose seasonal inactivated influenza vaccine (SIIV).

Family bereavement care interventions during the COVID-19 pandemic: a scoping review protocol.

Introduction: The COVID-19 pandemic has caused significant disruptions to daily social routines and to the lived experience of bereaved families. This article outlines the protocol for a scoping review of published studies to evaluate psychosocial and psychotherapeutic interventions intended to help family carers adjust to grief, loss and bereavement due to COVID-19. This review addresses one broad research question: 'What do we know about bereavement support interventions for family carers of COVID-19 victims?'

Methods And Analysis: The seminal framework by Arksey and O'Malley will guide the review process, which will cover both the qualitative and quantitative scientific literature on grief support during COVID-19.