Publications by authors named "Jaqueline Martins Morais"
Expression of VanA-type vancomycin resistance in a clinical isolate of Enterococcus faecium showing insertion of IS19 in the vanS gene.
Beatriz Nascimento Monteiro da Silva Adriana Rocha Faria Stephanie da Silva Rodrigues Souza Sabrina Santos Colodette Jaqueline Martins Morais
Int J Antimicrob Agents
April 2020
The characteristics of an unusual clinical isolate of Enterococcus faecium (CL-6729) showing insertion of IS19 (also known as ISEfm1) in the vanS gene while maintaining a constitutive VanA phenotype are described. This isolate was obtained from a hospital-acquired urinary tract infection, showed multidrug resistance by antimicrobial susceptibility testing, and belongs to ST78 based on multilocus sequence typing (MLST). Except for the vanS gene, all the other genes of the vanA gene cluster were intact according to conventional PCR, overlapping PCR and genome sequencing.
View Article and Find Full Text PDFArticle Synopsis
- - The study reports the identification and analysis of three vancomycin-resistant Enterococcus faecalis isolates carrying the vanB1 gene.
- - These isolates showed resistance mainly to chloramphenicol, erythromycin, and vancomycin, but were generally susceptible to other antimicrobial agents, with significant resistance to aminoglycosides.
- - This is the first documented instance of enterococcal strains with vanB genes being found in Brazil, highlighting a potential public health concern.