Taurine Chloramine decreases cell viability and cytokine production in blood and spleen lymphocytes from septic rats.

Taurine (Tau) is an abundant amino acid in polymorphonuclear leukocytes that react with hypochlorous acid to form taurine chloramine (TauCl) under inflammatory conditions. We investigated potential interactions between lymphocytes and TauCl in rats submitted to cecal ligation. Animals were divided into sham or CLP groups (24 or 120 h) to isolate lymphocytes from blood and spleen.

[Implications of the environment, conditions and organization of work on teacher health: a systematic review].

The state of health of the teacher is fundamental to the success of the teaching process. In addition to the intrinsic aspects, the scholastic context affects the well-being of the educator. The objective of this study was to identify the main psychosocial, structural and relational factors in the teaching profession.

Early pharmacological inhibition of angiotensin-I converting enzyme activity induces obesity in adulthood.

We have investigated early programming of body mass in order to understand the multifactorial etiology of obesity. Considering that the renin-angiotensin system (RAS) is expressed and functional in the white adipose tissue (WAT) and modulates its development, we reasoned whether early transitory inhibition of angiotensin-I converting enzyme activity after birth could modify late body mass development. Therefore, newborn Wistar rats were treated with enalapril (10 mg/kg of body mass) or saline, starting at the first day of life until the age of 16 days.