Publications by authors named "Jaqueline Gomes Lima"
Article Synopsis
- Brazil has experienced high COVID-19 cases and deaths, making Latin America a major pandemic epicenter, with early sustained virus transmission and ongoing gaps in understanding.
- Researchers analyzed over 17,000 near-complete SARS-CoV-2 genomes from across Brazil and Paraguay, finding multiple viral lineages predominantly imported from Europe before local transmission clusters emerged after November 2020.
- Effective genomic surveillance has been crucial in tracking the real-time spread of significant variants, such as Gamma (P.1) and Zeta (P.2), and understanding cross-border virus movement into Paraguay.
RT-PCR testing data provides opportunities to explore regional and individual determinants of test positivity and surveillance infrastructure. Using Generalized Additive Models, we explored 222,515 tests of a random sample of individuals with COVID-19 compatible symptoms in the Brazilian state of Bahia during 2020. We found that age and male gender were the most significant determinants of test positivity.
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- - Brazil became a major COVID-19 epicenter in Latin America by May 2021, experiencing high transmission rates and deaths, but gaps remain in understanding how the virus spreads nationally.
- - The study analyzes nearly complete SARS-CoV-2 genomes from Brazil and Paraguay, revealing that the initial wave was marked by multiple imported viral lineages mainly from Europe, leading to significant local transmission clusters.
- - As the pandemic progressed without effective restrictions, Brazil saw the emergence and spread of concerning variants like Gamma and Zeta, highlighting the need for extensive genomic surveillance in South America for better pandemic management and public health strategies.
Tracking the spread of SARS-CoV-2 variants of concern is crucial to inform public health efforts and control the ongoing pandemic. Here, we report genetic evidence for circulation of the P.1 variant in Northeast Brazil.
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