Venom's antinociceptive property in the primitive ant Dinoponera quadriceps.

Ethnopharmacological Relevance: In northeastern Brazil, Dinoponera (Ponerinae) ants macerate are used to treat ear ache and its sting, rheumatism, and back pain. Such a popular use is a relevant fact that called for experimental evaluation of the antinociceptive activity of Dinoponera venom.

Materials And Methods: Dinoponera quadriceps venom (DqV; 5-500 μg/kg; i.