Culture of in Different Carbon Sources to Induce In Vitro Cholesterol Consumption Leads to Alterations in the Host Cells after Infection: A Macrophage Proteomics Analysis.

During tuberculosis, uses host macrophage cholesterol as a carbon and energy source. To mimic these conditions, can be cultured in minimal medium (MM) to induce cholesterol consumption in vitro. During cultivation, consumes MM cholesterol and changes the accumulation of cell wall compounds, such as PIMs, LM, and LAM, which plays an important role in its pathogenicity.