"Acute responses to barefoot running are related to changes in kinematics, mechanical load, and inflammatory profile".

This study investigated the acute effects of barefoot (BF) running on biomechanical parameters and cytokine concentrations. Seventy-one habitually shod runners had biomechanical parameters evaluated during running shod (SH) and BF, while a sub-group of 19 runners had their inflammatory profile analyzed before and after a running session, using their habitual shoes or barefoot. Running BF changed spatiotemporal and joint kinematics, including the stride frequency (increased) and length (decreased), and foot strike pattern (more plantarflexed ankle at initial contact).

Influence of family history of hypertension on blood pressure and heart rate variability in young adults: a meta-analysis.

Purpouse: This meta-analysis evaluates the impact of family history of hypertension (FHH + ) on blood pressure (BP) and heart rate variability (HRV) in young adults.

Methods: Observational studies that evaluated adults (aged between 18 and 40 years) of both sexes, are without cardiometabolic disease diagnosis, are published in English, and are reporting on the influence of FHH + (father, mother, or both) on BP and HRV were included. In June 2021, we made a search of the electronic database MEDLINE (accessed by PubMed).

Inadequate positioning of central venous catheters inserted at intensive care units.

Objective: To evaluate the positioning of the distal tip of central venous catheters and the factors that contributed to inadequate positioning in patients admitted to intensive care.

Methods: This is a cross-sectional study, with a sample of 246 medical records of patients admitted to intensive care units. A catheter position analysis form was used as an instrument for data collection.

Silver nanoparticles formulations for healing traumatic injuries in oral mucosa of rats.

Objective: To evaluate formulations of 1 % silver (Ag) nanoparticles for treating traumatic lesions induced in the oral mucosa of rats, because these lesions are commonly observed in the dental clinic, and their therapeutic forms are scarce.

Methods: Wistar rats were punch-injured (two circular fragments, 4.0 mm in diameter) in the oral mucosa (one on each side), and were treated topically (twice per week) with the treatments/groups including: no injury, control, vehicle, diluted Ag, soluble Ag, and solid Ag.

Aerobic fitness influences cardiac autonomic modulation in police officers regardless of specific duties.

Purpose: This study assesses whether the specific duties of a police officer or aerobic fitness influences blood pressure (BP) and cardiac autonomic modulation.

Method: Police officers (n = 161) were divided into administrative and operational (34.72 ± 5.

Modulation of stress and immune response by Amblyomin-X results in tumor cell death in a horse melanoma model.

We have investigated Amblyomin-X-treated horse melanomas to better understand its mode of action through transcriptome analysis and the in vivo model. Amblyomin-X is a Kunitz-type homologous protein that selectively leads to the death of tumor cells via ER stress and apoptosis, currently under investigation as a new drug candidate for cancer treatment. Melanomas are immunogenic tumors, and a better understanding of the immune responses is warranted.

Reproducibility of Heart Rate Variability Indices at Post-maximal Exercise.

To analyze whether heart rate variability is reproducible after maximal exercise, 11 men (22.1±3.2 years) performed four incremental exercise tests followed by passive or active recovery.

Acute effects of moderate-intensity and high-intensity exercise on hemodynamic and autonomic reactivity to the cold pressor test in young adults with excess body weight.

Objective: To investigate the effects of a single session of moderate-intensity and high-intensity interval exercise in cardiovascular reactivity to the cold pressor test in young adults with excess body weight.

Methods: Twenty-two subjects with excess body weight (23 ± 2 years; 30.0 ± 3.

Isolated Obesity Is Not Enough to Impair Cardiac Autonomic Modulation in Metabolically Healthy Men.

Purpose: To evaluate whether excess body mass influences the heart rate variability (HRV) indexes at rest, and to correlate adiposity indicators and the aerobic fitness with cardiac autonomic variables in metabolically healthy young adults.

Method: In all, 41 untrained males (M= 21.80, SD = 2.

Reproducibility of Heart Rate Variability Threshold in Untrained Individuals.

The aim of this study was to evaluate the reproducibility of the heart rate variability threshold (HRVT) by different HRV indexes and determination criteria. 68 untrained participants, 17 women (24.09±4.

Higher blood pressure and lower cardiac vagal activity in obese young individuals in supine and seated position.

Background: Obesity triggers alterations in hemodynamic and autonomic control. There are few studies that investigate the effects of overweight and obesity in early adulthood on hemodynamic and autonomic variables.

Aim: The aim of this study was to determine whether overweight and obesity in young individuals cause alterations in hemodynamic parameters and heart rate variability (HRV) in supine and seated position, and to correlate these variables with anthropometric features.

Rapid genetic screening for major human leukocyte antigen risk haplotypes in patients with type 1 diabetes from Northeastern Brazil.

The aim of this study was to identify in the Brazilian population the frequency of human leukocyte antigen (HLA) DQ2.5 and DQ8 haplotypes conferring risk for type 1 diabetes (T1D), and to validate a new genotyping method aimed at cost reduction and automation. A total of 184 children and adolescents with T1D and 184 healthy individuals from Recife (northeastern Brazil) were analyzed using the conventional polymerase chain reaction-sequence-specific primers HLA genotyping and a newly described Tag-single-nucleotide polymorphism real-time polymerase chain reaction.