Publications by authors named "Janusz P"

Article Synopsis
  • Intraoperative neuromonitoring (IONM) is essential for ensuring patient safety during scoliosis surgery by monitoring spinal cord and nerve function through motor-evoked potentials (MEPs), with anesthesia type affecting the accuracy of these signals.
  • A systematic review was carried out, analyzing studies from major medical databases, which evaluated the impact of various anesthetic techniques on neuromonitoring during scoliosis procedures, narrowing down from 998 articles to 45 for detailed analysis.
  • The findings suggest that the Erector Spinae Plane Block (ESPB) offers significant advantages over traditional spinal and epidural anesthesia by improving neuromonitoring accuracy, reducing complications, and providing effective pain management, leading to better patient outcomes.
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  • A study compared the effectiveness of two nerve blocks (PENG and lumbar ESPB) for managing pain in kids undergoing hip surgeries while under spinal anesthesia.
  • Both techniques showed significantly lower pain scores, inflammatory markers, and reduced opioid use post-surgery compared to a control group.
  • The findings suggest that both blocks are effective options for relieving pain and minimizing stress responses after such surgeries in children.
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Background: Management of ankle joint deformity and instability are challenging issues in congenital fibular hemimelia (FH). This study aims to assess how much the SUPERankle procedure improves ankle alignment and provides durable ankle stability in patients with severe FH.

Methods: Seventeen children aged 53.

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Article Synopsis
  • The study evaluated the impact of perineural dexamethasone on pain relief, opioid use, and stress response metrics in children undergoing foot and ankle surgery.
  • Key findings included that a higher dose of dexamethasone (0.1 mg/kg) significantly extended the time before the first need for rescue opioids and increased motor block duration compared to lower doses and a control group.
  • No significant changes were observed in blood glucose levels or stress markers (NLR and PLR) among the different treatment groups post-surgery.
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  • The study investigated the effects of an ultrasound-guided erector spinae plane block (ESPB) on pain management and stress response in patients undergoing idiopathic scoliosis surgery, comparing it to standard analgesia methods.
  • Results indicated that patients receiving the ESPB reported significantly lower pain levels, required less opioid medication, and experienced reduced surgical stress, as measured by specific blood ratios (NLR and PLR).
  • The use of ESPB did not negatively impact intraoperative motor-evoked potentials, suggesting it is a safe and effective analgesic technique for this type of surgery.
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  • * In a study on mice with a genetic propensity for atherosclerosis, rhPRG4 treatment led to reduced aortic lesions and lower plasma-free cholesterol levels, along with changes in immune cell behavior that favored anti-inflammatory responses.
  • * Overall, the findings suggest that rhPRG4 serves not only as a lubricant but also as a potential therapeutic agent that can mitigate the inflammatory processes linked to heart disease.
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A practical solution to the incidental unreliability of intraoperative neuromonitoring (IONM) may be the simultaneous neurophysiological recording and control of the surgical field through a camera (the concept of "Real-time" IONM). During "Real-time" IONM, the surgeon is immediately warned about the possibility of damage to the neural structures during, but not after, standard idiopathic scoliosis (IS) corrective surgery procedures (the concept of "Surgeon-neurophysiologist" interactive, verbal IONM). This study aimed to compare the advantages, utilities, reliabilities, and time consumption of the two IONM scenarios.

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The relationships between the results of pre- and intraoperative motor evoked potential recordings during neuromonitoring and whether idiopathic scoliosis (IS) surgical correction improves the spinal efferent transmission have not been specified in detail. This study aims to compare the results of surface-recorded electromyography (EMG), electroneurography (ENG, M, and F-waves), and especially motor evoked potential (MEP) recordings from tibialis anterior muscle (TA) bilaterally in 353 girls with right idiopathic scoliosis (types 1-3 according to Lenke classification). It has not yet been documented whether the results of MEP recordings induced by transcranial single magnetic stimulus (TMS, pre- and postoperatively) and trains of electrical stimuli (TES; intraoperatively in T0-before surgery, T1-after pedicle screws implantation, and T2-after scoliosis curvature distraction and derotation following two-rod implantation) can be compared for diagnostic verification of the improvement of spinal cord neural transmission.

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  • The study investigates how erector spinae plane block (ESPB) affects inflammatory markers and recovery in patients undergoing lumbar decompression, comparing it to a sham block.
  • It involved 60 patients split into two groups, measuring outcomes like neutrophile-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), pain scores, and opioid use at 12 and 24 hours post-surgery.
  • Results showed that ESPB significantly lowered NLR and PLR, reduced pain, decreased opioid consumption, and improved functional recovery compared to the sham block.
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MicroRNAs (miRNAs) are highly conserved small non-coding RNAs, that modulate gene expression by targeting messenger RNA of many processes. Thus, miRNAs are key regulators of both physiological and pathological settings. Reliable results of quantitative miRNA evaluation depend on suitable reference genes (RGs) for data normalization.

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Introduction: Motor evoked potentials (MEPs) are currently considered as a more useful method for neurophysiological intraoperative monitoring than somatosensory evoked potentials in cases of surgery applied to patients with adolescent idiopathic scoliosis. The non-invasive approach is preferred to modify MEP recordings, criticizing, in many cases, the fundamentalism for neurophysiological monitoring based only on needle recordings. The aim of the review is to provide our own experience and practical guidelines with reference to neuromonitoring innovations.

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Purpose: The aim of this study was to determine the association between baby walker use and infant motor development, quality of gait, and potential development of lower extremity deformities.

Methods: An anonymous survey was conducted among 6874 parents and legal guardians regarding the use of baby walkers, their children's development, and the occurrence of lower extremity deformities and gait disorders. A total of 969 questionnaires were returned.

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Idiopathic scoliosis (IS) is a multifactorial disease with a genetic background. The association of Ladybird Homeobox 1 (LBX1) polymorphisms with IS has been proven in multiple studies. However, the epigenetic mechanisms have not been evaluated.

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Body posture develops during the growing period and can be documented using trunk photography. The study aims to evaluate the body posture in children aged 7-10 years undergoing a dedicated physical activities program versus regular school sport. A total of 400 children, randomly chosen from a cohort of 9300 participating in a local scoliosis screening program, were evaluated twice at a one-year interval.

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The study aimed to determine the impact of 6-month rigid brace on back muscle strength and endurance in adolescents with idiopathic scoliosis. Sixty-one girls, aged 7.0-16.

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The study aimed to carry on the process of the cultural adaptation of the Italian Spine Youth Quality of Life Questionnaire (ISYQOL) into Polish (ISYQOL-PL). The a priori hypothesis was: the ISYQOL-PL questionnaire is reliable and appropriate for adolescents with a spinal deformity. Fifty-six adolescents (mean age 13.

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