Radiomics from multisite MRI and clinical data to predict clinically significant prostate cancer.

Background: Magnetic resonance imaging (MRI) is useful in the diagnosis of clinically significant prostate cancer (csPCa). MRI-derived radiomics may support the diagnosis of csPCa.

Purpose: To investigate whether adding radiomics from biparametric MRI to predictive models based on clinical and MRI parameters improves the prediction of csPCa in a multisite-multivendor setting.

Soluble PD-L1 in Serum and Urine in Urinary Bladder Cancer Patients.

Soluble PD-L1 (sPD-L1) levels have been identified as a potential biomarker for various cancers, but its diagnostic and prognostic value in urinary bladder cancer (BC) remains to be fully elucidated. In this study, we investigated sPD-L1 levels in serum and urine samples from 132 patients with BC and compared them to 51 patients with hematuria (controls). The levels of sPD-L1 in serum and urine were determined using ELISA.

Diagnostic outcomes from transrectal and transperineal prostate biopsies - experiences from a Swedish tertiary care Centre.

Objective: The aim of this study was to compare diagnostic and infectious outcomes between MRI-guided transrectal (TR) and transperineal (TP) prostate biopsies, in order to evaluate implementation of local-anaesthesia TP biopsies in a Swedish university hospital setting.

Methods: In this non-randomized observational study, we recruited 105 patients who underwent TR or TP software-based MRI-ultrasound fusion prostate biopsies between April and August 2020. Information on outcome and covariates were obtained from hospital records.

[Current concepts of diverticular disease pathophysiology].

The first description of diverticular disease (DD) is dated on XVIIIth century. During last decades the DD prevalence continuously increases, especially in western countries. Nowadays, in developed countries, DD of the left colon is one of the most common diseases of gastro-intestinal tract.

[Thyroiditis in patients operated on for goiter].

Unlabelled: The paper is aimed at evaluating the frequency of incidence and the thyroiditis type in patients operated on for goiter. In the years 1989-2000, 5149 patients were operated on because of different thyroid disorders. The clinical data of 66 patients with thyroiditis, diagnosed in a post-operating histopathological examination, were subject to a retrospective analysis.