<b>Background and Objective:</b> Considering the many health benefits of fish oil, the potential of Indonesian fisheries needs to be mapped to find local fish oil sources that have the opportunity to be used as a source of omega-3 and 6. This research aimed to ascertain the glyceride profile of iridescent shark fish oil hydrolyzed by immobilized lipase from <i>Thermomyces lanuginosus</i> at the sn-1,3 position and identify the position of omega-3 and omega-6 fatty acids. <b>Materials and Methods:</b> To extract the fish oil from the iridescent shark, the soxhletation method was utilized.
View Article and Find Full Text PDFOpen Access Maced J Med Sci
November 2019
Aim: Free radicals produce from metabolism or enviromental which interact continously with biological system. Lour. herbs have been used as antioxidant and treat various diseases.
View Article and Find Full Text PDFOpen Access Maced J Med Sci
November 2019
Background: Fermented foods were favourable because of its properties in enhancing the shelf life, safety, function, sensory and nutrition. There are many fermented foods tested in vitro as an α-glucosidase enzyme inhibitor. Dengke naniura is one of Indonesia's traditional food made using fermentation.
View Article and Find Full Text PDFOpen Access Maced J Med Sci
November 2019
Background: Maximal physical activity can produce an imbalance between reactive oxygen species (ROS) and antioxidants which are possibly related to fatigue and tissue injury. One of the natural sources that contain antioxidants is virgin coconut oil (VCO).
Aim: This study aimed to determine the protective effects antioxidant of virgin coconut oil (VCO) treatment on urea and creatine level on maximum physical activity.
Open Access Maced J Med Sci
November 2019
Aim: The objective of the study was to evaluate protein expression in NIH 3T3 cells that are treated with virgin coconut oil (VCO) and hydrolysed of virgin coconut oil (HVCO) in vitro.
Methods: Coconut oil used in this study was virgin coconut oil (VCO) and VCO hydrolysed by (HVCO). NIH 3T3 cells (5x10 cells/well) were seeded in nine wells and incubated for overnight, then divided into three groups.
Open Access Maced J Med Sci
November 2019
Aim: This study was aimed to prepare in situ cross-linked N-maleoyl chitosan - oxidised sodium alginate (MCS - OSA) hydrogel loaded with metronidazole (MTZ) for drug delivery applications.
Methods: The hydrogel was prepared by in situ cross-linking via Schiff base reaction between amine (-NH2) groups from MCS and aldehyde (-CHO) groups from OSA at the different ratio, and the MTZ was loaded into the hydrogels along with the gelatin processes.
Results: The highest drug entrapment efficiency (DEE) was exhibited by MTZ-H3 (5: 5) with DEE of 99.
Aim: This study aims to determine the effect of hydrolysed virgin coconut oil (HVCO) to increase cell proliferation, COX-2 expression of NIH 3T3.
Methods: The sample used was Virgin Coconut Oil (VCO). VCO was partially hydrolysed using lipase from (active on sn-1,3 position) to produce hydrolysed VCO (HVCO) composed of free fatty acids, 2-monoglycerides.
Background: Nitrosamine is a carcinogen and the maximum level in processed meat products set by WHO.
Aim: The purpose of this study was to determine nitrosamine levels in meat products in Medan City and compared nitrosamine levels with standards set by WHO.
Methods: The samples analysed were obtained from Berastagi Supermarket, sausages, burgers, corned beef and smoked beef.
Open Access Maced J Med Sci
March 2019
Background: The use of medicinal plants is increasing in several decades for relief many diseases. Indonesia consists of thousands of islands with various plants and the manners of the community using plants as a treatment for every disease traditionally.
Aim: Cytotoxic activity of ethyl acetate fraction (EAF) of fruit was tested towards T47D breast cancer cells.
Background: Excessive production of oxygen free radicals and imbalance in the mechanisms responsible for antioxidant protection may result in the onset of many diseases including breast cancer. Objective: To evaluate antiproliferative and antioxidant activity of an ethylacetate fraction (EAF) of Picria fel-terrae Lour. Herbs in the T47D cell line.
View Article and Find Full Text PDFAsia Pac J Clin Nutr
October 2002
Accumulated evidence from experimental and epidemiological studies indicates that there is a low risk of degenerative diseases, cardiovascular disease, hypertension, cataract, stroke and, in particular, cancers in people with a high intake of fruit and vegetables. This protective effect is assumed to be associated mainly with the antioxidant activities of either individual or interacting bioactive components present in the fruits and vegetables, and with other biochemical and physical characteristics of the identified and unknown bioactive components. The implicated bioactive components present in citrus fruits include vitamin C, beta-carotene, flavonoids, limonoids, folic acid, and dietary fibre.
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