Driving factors of energy related CO emissions at a regional level in the residential sector of Iran.

Iran has increased its CO emissions significantly during the past few decades. The household sector in Iran contributes one of the largest sectors of CO emissions. Despite this significant contribution, the existing policies have predominantly concentrated on large-scale initiatives while overlooking the regional role in shaping and implementing these plans.

A randomized, placebo-controlled phase 3 trial (Study SB-767905/013) of alvimopan for opioid-induced bowel dysfunction in patients with non-cancer pain.

Unlabelled: The balance between the pain relief provided by opioid analgesics and the side effects caused by such agents is of particular significance to patients who take opioids for the long-term relief of non-cancer pain. The spectrum of signs and symptoms affecting the gastrointestinal (GI) tract associated with opioid use is known as opioid-induced bowel dysfunction. Alvimopan is an orally administered, systemically available, peripherally acting mu-opioid receptor (PAM-OR) antagonist, approved in the US for the management of postoperative ileus in patients undergoing bowel resection (short-term, in-hospital use only).