Evening and morning plasma levels of protein S100B in patients with obstructive sleep apnea.

Objective: Responsible for sleep brain perfusion changes, obstructive sleep apnea (OSA) constitutes a cardiovascular risk. To find out about any diffuse damage to the brain tissue, we studied the S100B protein, whose serum level is known to rise in stroke and craniocerebral trauma.

Methods: 60 men (mean age 51.