Collagen 1 gel may improve the regenerative capacity of minced adult and preosteoarthritic cartilage.

Purpose: Minced cartilage implantation (MCI) is an evolving technique for the treatment of osteochondral lesions. It was hypothesised that mincing of cartilage may affect chondrocyte viability and phenotype and that embedding in collagen 1 gel results in an improved outcome. The objective of this study was to evaluate the impact of cartilage mincing and whether collagen 1 gel mediates beneficial effects on the chondrocyte phenotype and viability.

In vivo corrosion on retrieved hip endoprostheses and in vitro effects of corrosion products on bone mineralization.

In vivo corrosion of modular endoprostheses remains a great concern, as the release of heavy metal ions can impair the implant's service life and the wellbeing of the patient. The detailed corrosion mechanisms that occur in vivo are so far not completely understood. In this context, the effects of implant released cobalt (Co) and chromium (Cr) ions on osteoblast mineralization and gene expression have not been investigated extensively.

Microglial CD74 Expression Is Regulated by TGFβ Signaling.

Microglia play important roles during physiological and pathological situations in the CNS. Several reports have described the expression of in disease-associated and aged microglia. Here, we demonstrated that TGFβ1 controled the expression of in microglia in vitro and in vivo.

Characterization of the Leucocyte Immunoglobulin-like Receptor B4 () Expression in Microglia.

As resident innate immune cells of the CNS, microglia play important essential roles during physiological and pathological situations. Recent reports have described the expression of in disease-associated and aged microglia. Here, we characterized the expression of in microglia in vitro and in vivo in comparison with bone marrow-derived monocytes and peritoneal macrophages in mice.