Publications by authors named "Janni Dausell"
Cell Physiol Biochem
September 2013
Article Synopsis
- The study investigates the role of specific mutations in the CysLT1 receptor on desensitization and regulatory volume decrease (RVD).
- Four mutations were created in the receptor to assess their impact on calcium-activated currents in response to LTD4, a signaling molecule.
- Results showed that certain mutations impacted desensitization, with specific double mutations preventing it, indicating that phosphorylation at key sites leads to receptor desensitization and affects cell volume regulation.
