[Standardised in-hospital mortality decreasing over time].

Objective: To study the changes in standardised in-hospital mortality in the period 2005 to 2010.

Design: Retrospective, descriptive study.

Method: Data from the National Medical Registration (LMR) for the period 2005 to 2010 were used to calculate a time-series of the standardised in-hospital mortality rate.

Setting and registry characteristics affect the prevalence and nature of multimorbidity in the elderly.

Objective: The aim of the study was to investigate how settings and registry characteristics affect the prevalence and nature of multimorbidity in elderly individuals.

Study Design And Setting: We used data from three population-based studies, two general practitioner registries, one hospital discharge register, and one nursing home registry to estimate the prevalence of multimorbidity. Individuals aged 55 years and over were included.

Testing the Simple Lifestyle Indicator Questionnaire: Initial psychometric study.

Objective: To carry out initial psychometric testing on the Simple Lifestyle Indicator Questionnaire (SLIQ).

Design: Self-administered questionnaire to obtain data for test-retest reliability, for Cronbach alpha testing on completed questionnaires, and for blinded external validity testing.

Setting: Kingston, Ont, and surrounding area.

Metabolic syndrome in a family practice population: prevalence and clinical characteristics.

Objective: To determine the prevalence and clinical characteristics of metabolic syndrome in a family practice population.

Design: Chart abstraction and patient interviews.

Setting: Family Medicine Centre in Kingston, Ont.

Diet, lifestyle and risk of K-ras mutation-positive and -negative colorectal adenomas.

K-ras mutation-positive (K-ras+) and -negative (K-ras-) colorectal adenomas may differ clinically and pathologically. As environmental compounds may cause mutations in the growth-related K-ras oncogene or affect clonal selection depending on mutational status, we evaluated whether the aetiology of K-ras+ and K-ras- adenomas differs. K-ras mutations in codons 12 and 13 were assessed in colorectal adenoma tissue (K-ras+: n = 81, K-ras-: n = 453).