Publications by authors named "Janne P Karhunen"

Objective: Follow-up studies of patients surviving emergency resternotomy, open cardiac massage, and additional emergency cardiac surgery following coronary artery bypass grafting (CABG) remain sparse and studies focusing on health-related quality of life are lacking. Our aim was to elucidate the long-term course of patients experiencing this hazardous complication.

Methods: Between 1988 and 1999, 76 patients suffered sudden hemodynamic collapse following isolated CABG.

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Sudden unexpected postoperative hemodynamic collapse with a high mortality develops in 1-3% of patients undergoing coronary artery bypass surgery (CABG). The contribution of surgical graft complications to this serious condition is poorly known and their demonstration at autopsy is a challenging task. Isolated CABG was performed in 8,807 patients during 1988-1999.

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Article Synopsis
  • The study aimed to identify predictive factors for sudden hemodynamic collapse after CABG surgery, a severe complication associated with high death rates.
  • A retrospective analysis compared 76 patients who experienced collapse with a matched control group, revealing that a majority of collapses occurred within the first five postoperative hours and caused a significantly higher in-hospital mortality rate of 46%.
  • Key findings included prolonged cardiopulmonary bypass times and lower cardiac indices and acid-base values in the collapsed group, indicating that these factors may predict complications and the need for additional support post-surgery.
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