A Comprehensive Study to Unleash the Putative Inhibitors of Serotype2 of Dengue Virus: Insights from an In Silico Structure-Based Drug Discovery.

Dengue fever is a mosquito-borne disease that claims the lives of millions of people around the world. A number of factors like disease's non-specific symptoms, increased viral mutation, growing antiviral drug resistance due to reduced susceptibility, unavailability of an effective vaccine for dengue, weak immunity against the virus, and many more are involved. Dengue belongs to the Flaviviridae family of viruses.

Correction: Oxa-376 and Oxa-530 variants of β-lactamase: computational study uncovers potential therapeutic targets of .

[This corrects the article DOI: 10.1039/D2RA02939A.].

Oxa-376 and Oxa-530 variants of β-lactamase: computational study uncovers potential therapeutic targets of .

Antimicrobial resistance is a major global health crisis, resulting in thousands of deaths each year. Antibiotics' effectiveness against microorganisms deteriorates over time as multidrug resistance (MDR) develops, which is exacerbated by irregular antibiotic use, poor disease management, and the evasive nature of bacteria. The World Health Organization has recognized multidrug resistance as a critical public health concern, and has been at the center of attention due to its ability to develop multidrug resistance (MDR).