Publications by authors named "Janna-Maija Mattila"
Article Synopsis
- A study at Turku University Hospital examined trends in children hospitalized with influenza over a 25-year period (1993-2018).
- The median age of hospitalized children increased significantly from 1.3 to 3.3 years, with a shift in age distribution showing fewer children under 2 and more aged 6-15.
- Hospitalization rates for younger children decreased by 49%, whereas rates for older children increased by 194%, and the average length of stay was reduced from 2 days to 1 day.
Oseltamivir treatment of influenza A and B infections in infants.
Influenza Other Respir Viruses
September 2021
Background: Oseltamivir treatment is currently the only way of managing influenza in young infants for whom influenza vaccines are not licensed, but little data exist on the effectiveness of the treatment in this age group.
Methods: In a prospective study, we enrolled 431 newborn infants and followed them up for 10 months during their first respiratory season (September 2017-June 2018). During each respiratory illness, we examined the infants and obtained nasopharyngeal specimens for determination of the viral etiology.
Article Synopsis
- * The findings revealed that the incidence of RSV illness was 328.4 per 1,000 infants, with those having siblings being nearly twice as likely to get infected.
- * Complications from RSV were common, as 76.9% of infected infants developed acute otitis media, and nearly 7% were hospitalized, highlighting the significant outpatient burden of RSV in infants.
Background: Every year, influenza viruses infect millions of children and cause an enormous burden of disease. Young children are at the highest risk for influenza-attributable hospitalizations. Nevertheless, most young children are treated as outpatients, and limited data are available on the burden of influenza in these children.
View Article and Find Full Text PDFComparative Severity of Influenza A and B Infections in Hospitalized Children.
Pediatr Infect Dis J
June 2020
Background: Influenza A viruses are conventionally thought to cause more severe illnesses than B viruses, but few studies with long observation periods have compared the clinical severity of A and B infections in hospitalized children.
Methods: We analyzed the clinical presentation, outcomes and management of all children <16 years of age admitted to Turku University Hospital, Finland, with virologically confirmed influenza A or B infection during the 14-year period of 1 July 2004 to 30 June 2018. All comparisons between influenza A and B were performed both within predefined age groups (0-2, 3-9 and 10-15 years) and in all age groups combined.