Publications by authors named "Janna Ore Nugent"
Deep learning for cancer type classification and driver gene identification.
BMC Bioinformatics
October 2021
Article Synopsis
- Genetic information is increasingly used for predicting cancer types and subtypes, but existing methods mainly focus on somatic mutations and have limitations due to study size.
- The proposed method, DeepCues, is a deep learning model that uses convolutional neural networks to analyze raw cancer DNA sequencing data for more accurate cancer classification and identifying significant genes.
- DeepCues achieved a 77.6% accuracy in classifying seven major cancers from TCGA data and showed a substantial improvement over traditional methods, demonstrating its effectiveness in predicting cancer types and finding relevant genes.