Retinal Vasoproliferative Tumor in Association with Neurofibromatosis Type 1.

Retinal vasoproliferative tumor is an uncommon benign vascular tumor that most often occurs sporadically. Vision loss can occur secondary to retinal fibrosis, subretinal exudation, and neovascular glaucoma. This report describes a functionally monocular patient with neurofibromatosis type 1 who had a vasoproliferative tumor with neovascularization of the iris that was successfully treated with intravitreal bevacizumab and cryotherapy.

[ABO/H blood groups and factor V Leiden].

Background: Jick and his co-workers published in 1969 an observation showing the prevalence of blood group 0 being lower in people with thrombosis than in the healthy population. During the next years this finding was several times confirmed. The aim of our work was to answer the question on the distribution of blood groups in individuals with thrombophilia compared to the control group and whether the non-0 blood group increases the thrombosis risk in factor V Leiden carriers.