(1) Background: A free gingival graft (FGG) is a common technique used to reconstruct or enhance the area of keratinized mucosa, while a connective tissue graft (CTG) is utilized to boost soft tissue thickness, thereby promoting stability in interproximal marginal bone levels. Most reported complications following FGG procedure are associated with the donor site. In addition to a painful, open wound in the palate, the most frequent complications linked to FGG harvesting include excessive bleeding, postoperative bone exposure, and recurrent herpes lesions.
View Article and Find Full Text PDFMotor imagery (MI) encompasses kinesthetic motor imagery (KMI), internal visual-motor motor imagery (IVMI), and external visual-motor motor imagery (EVMI). This study explored α/β oscillations during MI of left-/right-hand movement from KMI/IVMI/EVMI perspectives in a group of left- (N = 20) and right-handed (N = 20), volunteers selected based on their laterality quotient (RH > 80; LH > -80). We analyzed changes in the power of α/β oscillations from visual- and motor-related clusters of independent components, connectivity (imaginary part of coherence; ICOH) between electroencephalographic activity from selected regions of interest (ROIs), and the correctness of the MI.
View Article and Find Full Text PDFBackground: The use of immunotherapy in treatment of non-small cell lung cancer (NSCLC) patients with the gene mutations is an area of active research and is an item of clinical trials. While mutations are relatively infrequent in NSCLC patients, comprising approximately 1-3% of cases, the V600E substitution stands out as the most prevalent subtype of mutations. The presence of this mutation in cancer cells qualifies the patients for first-line therapy with BRAF and MEK inhibitors.
View Article and Find Full Text PDFBackground: Emergency departments (EDs) worldwide are dealing with overcrowding, system fragmentation, and coordination problems, which impact patient wait times, staff job satisfaction, and patient outcomes. Inappropriate ED visits, particularly those for low acuity conditions, exacerbate these challenges. However, the motivations behind these visits are poorly understood, with limited data from the patient perspective.
View Article and Find Full Text PDF: Implant treatment in patients who require teeth extraction due to periodontitis presents a significant challenge. The consideration of peri-implantitis is crucial when planning the placement of dental implants. The predictability of implant treatment relies on the suitability of both hard and soft tissue quality.
View Article and Find Full Text PDFThis paper discusses the potential of additive printing, the risks it poses to users' health (including 3D printer operators) and the effects of chemical substances released during the printing based on the available and studies. It was shown that substances emitted during printing with the commonly used acrylonitrile butadiene styrene filament in additive manufacturing might have carcinogenic, hepatotoxic and teratogenic effects, as well as toxic effect on the respiratory system. The latest research on the mechanism of formation of particles and volatile organic compounds during 3D printing, the parameters affecting their potential emission, and trends in reducing these hazards are indicated.
View Article and Find Full Text PDFOlder adults are often overlooked in decision making processes despite the detrimental effects on their well-being. The representation of older adults in investigations and initiatives is needed so that the issues they face, today and in the future, can be resolved through partnership and their active involvement. The aim of this article is to describe a participatory process for conducting a needs assessment (NA) and the contributions and opportunities of partnering older adults to shape community services and support r older adults.
View Article and Find Full Text PDFIntroduction: Pembrolizumab combined with chemotherapy has become the standard of care for patients with non-small-cell lung cancer (NSCLC) and the expression of programmed death ligand 1 (PD-L1) in <50% of tumour cells (TC).
Methods: We evaluated the efficacy of the treatment in real-world practice, paying attention to the predictive factors, with a special focus on low level of PD-L1 expression. This study is a multicenter retrospective analysis of patients with stage IV NSCLC.
Objectives: To compare artificial intelligence (AI)-driven web-based platform and manual measurements for analysing facial asymmetry in craniofacial CT examinations.
Methods: The study included 95 craniofacial CT scans from patients aged 18-30 years. The degree of asymmetry was measured based on AI platform-predefined anatomical landmarks: sella (S), condylion (Co), anterior nasal spine (ANS), and menton (Me).
Purpose: The interim analysis of the phase IIIb LUCY trial demonstrated the clinical effectiveness of olaparib in patients with germline BRCA-mutated (gBRCAm), human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (mBC), with median progression-free survival (PFS) of 8.11 months, which was similar to that in the olaparib arm of the phase III OlympiAD trial (7.03 months).
View Article and Find Full Text PDFRationale And Objectives: Evaluation of the diagnostic value of linearly blended (LB) and virtual monoenergetic images (VMI) reconstruction techniques with and without metal artifacts reduction (MAR) and of adaptive statistical iterative reconstructions (ASIR) in the assessment of target vessels after branched/fenestrated endovascular aortic repair (f/brEVAR) procedures.
Materials And Methods: CT scans of 28 patients were used in this study. Arterial phase of examination was obtained using a dual-energy fast-kVp switching scanner.
When species spread into new regions, competition with native species and predatory-prey relationships play a major role in whether the new species can successfully establish itself in the recipient food web and become invasive. In aquatic habitats, species with a metagenetic life cycle, such as the freshwater jellyfish with benthic polyps and planktonic medusae, have to meet the requirements of two distinct life stages occurring in two habitats with different food webs. Here, we examined the trophic position of both life stages, known to be predatory, and compared their niches with those of putative native competitors using stable isotope analysis.
View Article and Find Full Text PDFObjective: This phase 3 study was undertaken to investigate the efficacy and safety of lenabasum, a cannabinoid type 2 receptor agonist, in patients with diffuse cutaneous systemic sclerosis (dcSSc).
Methods: A multinational double-blind study was conducted in 365 dcSSc patients who were randomized and dosed 1:1:1 with lenabasum 20 mg, lenabasum 5 mg, or placebo, each twice daily and added to background treatments, including immunosuppressive therapies (IST).
Results: The primary end point, the American College of Rheumatology combined response index in dcSSc (CRISS) at week 52 for lenabasum 20 mg twice a day versus placebo, was not met, with CRISS score of 0.
Self-concept clarity (SCC) refers to the extent to which self-beliefs are clearly and confidently defined, internally consistent, and stable. While there is an abundance of research showing an association between SCC, well-being, and effective self-regulation, there is little knowledge about how SCC relates to basic cognitive processes such as attention and memory. Drawing on the attentional function theory of cognitive control, we hypothesized that low SCC is associated with greater attentional control during a trait assessment task.
View Article and Find Full Text PDFObjectives: The objective of this prospective study was to evaluate the virtual monoenergetic images (VMI) and virtual noncontrast (VNC) phase in the detection of endoleaks after endovascular abdominal aortic repair (EVAR). The potential dose reduction of abbreviated examination protocols was calculated.
Materials And Methods: Ninety-seven patients after the EVAR procedure were enrolled in this study.
The pressure drop dynamics during the filtration of three-component mixture aerosols are investigated and compared with two and single-component aerosols. The main area of interest is the effect of the addition of a small quantity of liquid (oil) and solid (soot) particles during the filtration of aerosol containing water mist. In addition, calculations of the change in filter mass during oil aerosol filtration have been carried out and compared with the experimental results.
View Article and Find Full Text PDFTissue flossing is an increasingly popular method in physiotherapy and sports. There is a belief that tissue flossing can improve range of motion and muscle strength, shorten muscle recovery time, and reduce the risk of injury. The aim of this study was to analyse the effectiveness of tissue flossing for immediately improving muscle strength in recreational athletes when it is performed during warm-up.
View Article and Find Full Text PDFThis work presents the application of an experimental nematic liquid crystal (LC) mixture (1929) in a large aperture lens. The LC material is composed of terphenyl and biphenyl derivatives compounds with an isothiocyanate terminal group and fluorinated lateral substituents. The substitution with a strongly polar isothiocyanate group and an aromatic rigid core provides [Formula: see text]-electron coupling, providing high birefringence ([Formula: see text] at 636 nm and 23 °C) and low viscosity ([Formula: see text] = 17.
View Article and Find Full Text PDFSeveral studies have shown that eveningness is positively related to both depressive and anxiety symptoms. However, little is known about factors that may play a protective role against the undesirable emotional consequences of evening preference. Thus, in the present study, we explored the moderating effects of dispositional mindfulness on the relationship between morningness-eveningness and the presence of depressive symptoms, as well as between morningness-eveningness and the presence of anxiety symptoms.
View Article and Find Full Text PDFIn 2019, the European Committee for Standardization (CEN) initiated work on the preparation of a strategy for air quality monitoring at workplaces. The aim was to determine the concentrations of nano-objects and their aggregates and agglomerates (NOAA) by means of direct measurements using low-cost sensors. There is a growing need for low-cost devices that can continuously monitor the concentrations of nanoparticles, and that can be installed where nanoparticles are used or created spontaneously.
View Article and Find Full Text PDFIn this work, a technique to generate aspherical liquid crystal lenses with positive and negative optical power is experimentally demonstrated. The main enabling element is a micro-metric electrode with variable spatial size. This produces a decreasing resistance towards the lens centre that generates the desired voltage/phase profiles.
View Article and Find Full Text PDFThe Relational Depth Frequency Scale (RDFS) is a 6-item measure to assess the impact of relational depth experiences on psychotherapeutic outcomes. To date, the RDFS has only been validated in online samples of clinical and non-clinical individuals. This study aimed to examine the psychometric properties of the RDFS in clinical dyads of clients and psychotherapists.
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