Publications by authors named "Janjira Inprasit"

Ethnopharmacological Relevance: Sa-Tri-Lhung-Klod (ST) remedy is a Thai traditional remedy used in obstetrics and gynecology to reduce inflammation and nourish the body post-partum. In Thai traditional medicine (TTM), there is a theory of formulating drugs based on the four elements and the tastes of herbs for use in treating diseases.

Aims Of Study: To determine relationships between taste theory and pharmacological properties for the anti-inflammatory effect of ST remedy and its chemical constituent components.

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Article Synopsis
  • The Kheaw-Hom (KH) remedy, a traditional Thai medicine known for treating fever and inflammation in children, has not previously been studied for its anti-inflammatory effects or bioactive compounds.
  • This study aimed to assess the in vitro and in vivo anti-inflammatory properties of KH remedy and its key compound, ethyl p-methoxycinnamate (EPMC), while investigating the connection between flavor and ethnopharmacological functions based on traditional Thai medicine theory.
  • Results revealed that a specific preparation of KH (KHP-h) exhibited the highest EPMC content and effectively reduced inflammatory markers in both cell cultures and in vivo experiments, indicating its potential as a therapeutic anti-inflammatory agent.
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  • The Prasachandaeng (PSD) remedy, used in Thailand for centuries to reduce fever, was found to have significant antipyretic effects similar to acetaminophen (ACP) in a study involving rats.
  • When examining liver safety, various PSD forms showed no signs of damage, with liver function tests indicating normal levels and less hepatotoxicity compared to ACP.
  • Histopathological analysis confirmed these findings, demonstrating that both PSD powder and ethanol extract were effective at lowering fever without harmful effects on liver health over a seven-day period.
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Expression of chemokine receptor CX3CR1 is reportedly restricted to several cell types including natural killer cells, cytotoxic T cells, monocytes, and macrophages. However, its expression and function on exosomes, which are nanosized extracellular vesicles known to act as mediators of intercellular communications, remain unclear. Here, we investigated CX3CR1 expression on exosomes isolated from various cell types.

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Background: Sa-Tri-Lhung-Klod is a Thai traditional medicine remedy for postpartum in the lists of The National Drug List ofHerbal Medicine Products AD. It consists ofseventeen herbs and were obtained by maceration and used in the form of liquor for women's health care such as treatment ofamenorrhea, menopause and blood tonic. In addition, it also usedfor postpartum care for being anti-inflammation in postpartum and prevention of cancer in women.

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