Observational multicentric study to evaluate efficacy, adverse effects and acceptance of bowel cleansing prior to colonoscopy with sodium picosulfate / magnesium citrate formulation CitraFleet®.

The various efficient methods available for bowel preparation prior to colonoscopy differ in patient acceptance. Combining the laxative sodium picosulfate with hyperosmotic magnesium citrate, used in this study in the formulation CitraFleet(®), allows the uptake of the purgative substances as a solution of low volume. This observational study with 737 patients evaluated efficacy of bowel preparation, potential side or adverse effects and patient acceptance of this medicinal product when used by resident physicians in Germany.

Severity and duration of mental deficiency symptoms after intravenous administration of propofol.

The severity and duration of cognitive performance capacity deficits after intravenous administration of propofol were determined using the validated psychological test procedure syndrome short test (SKT), a simple reaction test and original driving licence exam questions. The test battery was performed before, immediately after, as well as 1 and 2 h after propofol administration in 23 persons. Immediately after propofol anaesthesia, six individuals had a slight performance loss, and four subjects showed mild deficits, consistent with medium organic neuropsychologic disorder or dementia.

Eradication of Helicobacter pylori with pantoprazole and two antibiotics: a comparison of two short-term regimens.

Background: High rates of Helicobacter pylori eradication can be achieved by combining proton pump inhibitors with two antibiotics. However, in the search for an optimal therapy a direct comparison of different regimens is necessary.

Methods: For this open study, 331 patients with duodenal ulcer were screened and randomly allocated to either pantoprazole 40 mg b.

Concentrations of various arachidonic acid metabolites in menstrual fluid are associated with menstrual pain and are influenced by hormonal contraceptives.

In a pilot study we investigated the association between concentrations of various eicosanoids in menstrual blood with pain and oral contraceptive use. Menstrual fluid was collected on tampons by 12 women who did not use an oral contraceptive but suffered from slight primary dysmenorrhea and by three pain-free women who used an oral contraceptive. Eicosanoids (cyclooxygenase products: 6-ketoprostaglandin F1 alpha, thromboxane B2, prostaglandin E2, prostaglandin F2 alpha, 13,14-dihydro-15-ketoprostaglandin F2 alpha, 12-hydroxy-heptadecatrienoic acid; lipoxygenase products: 5-, 12-, 15-hydroxy-eicosatetraenoic acid (HETE), leukotriene B4, leukotriene C4, leukotriene D4, leukotriene E4) and female sex steroids (17 beta-estradiol and progesterone) were analyzed by the combined use of high-performance liquid chromatography and radioimmunoassay.

Measurement of eicosanoids in menstrual fluid by the combined use of high pressure chromatography and radioimmunoassay.

Methods are described for the quantification of various eicosanoids (cyclooxygenase products: 6-KETO, TXB2, PGE2, PGF2 alpha, DHK; lipoxygenase products: 5-, 12-, 15-HETE, LTB4, LTC4, LTD4, LTE4) in menstrual blood collected by tampons. Samples were extracted with acidified ethanol. After purification by SEP-PACK C18 columns, the compounds were separated by reversed phase HPLC using a ternary gradient system.

[Surgical treatment of invasive malignancies of the vulva using CO2 laser].

In a retrospective study, we analysed 26 CO2-laser vulvectomies within the observation period between 1982 and 1990. Indications for vulvectomies were invasive malignancies of the vulva, FIGO stage I to III. 91.

[Mucoviscidosis screening with immunoreactive trypsin].

Up to now 49,116 immunoreactive trypsin (IRT) measurements have been carried out in Austrian newborns in the first week of life. Related to provisionally chosen cut-off points, 301 newborns (0.61%) showed an elevated IRT value; 253 of them were successfully recalled.

[Prognostic factors in stage Ia-IIb invasive cervix cancer after radical hysterectomy with special reference to stroma reaction].

158 cases of invasive carcinoma of the uterine cervix stages Ia to IIb were analysed with respect to the following prognostic criteria: histological stage, presence of nodal metastases, vascular space invasion and inflammatory stromal reaction at the periphery of the tumor. The assessment of these criteria was correlated to the prevalence of tumor recurrence. In cases with absent nodal metastases, a significant increase of tumor recurrence in stage IIb compared to other stages was noted.

[Morphologic and functional long-term results after Vecchietti operation for the formation of a neovagina].

For creation of a neovagina in patients with congenital vaginal agenesis, a variety of operative procedures are recommended. Basically, two different procedures are described: (1) Application of pressure or traction to the perineum and (2) plastic-surgical operations. Since 1981, the 2nd Department of Obstetrics and Gynecology, Vienna, utilises the method described by Vecchietti.

[The role of intestinal resection in primary surgery of ovarian carcinoma].

In most ovarian cancer cases complete resection of the tumour masses is not possible, and tumour reduction at the primary operation has been shown to improve survival. In some cases optimal tumour reduction is only possible by resecting intestinal structures, and it remains to be shown whether aggressive approaches are justified. The impact of intestinal resection, among other prognostic factors, was analysed in 104 patients undergoing primary operation for ovarian cancer.

[Therapeutic aspects of trichomonas infection of the female genitals].

Infection with trichomonas is a common event in patients in gynecologic practice. In patients in an outpatient department the incidence of trichomonas infection was 7%, in cases with other genital infections 16%. Especially in alcalic vaginal milieu and in Gardnerella infections higher rates of trichomonas could be observed.

[Effect of nitrendipine on the function of the upper gastrointestinal tract].

A double-blind crossover-trial comparing the influence of orally administered nitrendipine and placebo on the function of the upper gastrointestinal tract was carried out in ten healthy volunteers. Esophageal motility, intestinal transit time, size and motility of the gallbladder, serum gastrin levels and gastric secretion (basal and after stimulation with pentagastrin) were determined. No statistically significant differences between nitrendipine and placebo could be observed.

[Surgical correction of uterus abnormalities: experiences with the Tompkins method].

In the last 10 years, 12 abdominal metroplasties (Tompkins) were performed at the 2nd Department of Obstetrics and Gynaecology, Vienna. All patients had a history of at least 2 spontaneous abortions, caused by a deformity of the uterus. The operation according to Tompkins, is technically simple and does not result in a defect in the uterus.

Evaluation of a simple and fast self-test for urine luteinizing hormone.

Ovulation can be predicted by measuring the midcycle urine luteinizing hormone surge with a simple 5-minute enzyme-immunoassay. This assay has proved to be suitable for self-tests with a sensitivity of about 90% and a specificity of 100% in unstimulated and clomiphene citrate stimulated cycles. Whereas a reference method (hemagglutination test) yielded better sensitivity, its specificity was markedly worse.

[Metoclopramide antagonizes dopamine-induced inhibition of lower esophageal sphincter pressure in the awake beagle].

Different contradictory results, even in the same species of the DOP-effect on LESP have been reported. The aim of the present studies was to evaluate the effect of DOP on LES in purebread male beagles and whether in could be antagonised by the DOP-antagonist MCP. The LESP in beagles is sensitive to dopamine (DOP) and its "antagonist", metoclopramide (MCP).

[Second look operation from the current viewpoint].

Tumor reduction or elimination during primary surgery is the most important goal to aim at. Platinum-containing poly-chemotherapies led to an increase in remissions. However, highly advanced technologies (computed tomography, ultrasonography, nuclear magnetic resonance) and combined analysis of tumor markers are not sensitive enough to evaluate tumor-free status.