Genetic mechanisms of electroconvulsive therapy response in depression.

Electroconvulsive therapy (ECT) is known to be one of the most effective treatments for managing depression and other severe mental illnesses. Nevertheless, the exact mechanisms underlying response to ECT remain uncertain. This mini-review presents clinical findings regarding the role of genetic factors in the aetiology of the ECT response.

A Survey of the Practice of Electroconvulsive Therapy in South Africa.

Objectives: The aim of this study was to describe the contemporary practice of electroconvulsive therapy (ECT) in South Africa.

Methods: A 36-item questionnaire was sent to all hospitals that practiced ECT in a 12-month period between 2011 and 2012.

Results: Forty-two institutions had an ECT machine on site, but 13 institutions reported nonuse.