Publications by authors named "Janina Klasen-Sansone"
Article Synopsis
- * A study of 76 children undergoing MRI screening for leukemia diagnosis found that 9.2% had osteonecrotic lesions, primarily in the hips and knees, at the beginning of treatment.
- * Over a six-month period, the severity and number of osteonecrotic lesions in patients showed unpredictable changes, with some worsening and others improving, but no significant differences were found in patient characteristics between those with and without ON at diagnosis.
Osteonecrosis (ON) is a debilitating side effect of anti-leukemic treatment. Thus far, the role of leukemic infiltration (LI) of bone is unclear. The first 30 children aged ≥10 years, who were enrolled in the ongoing OPAL trial and had MRI studies at diagnosis and at 6 months, were analyzed.
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