Publications by authors named "Janin-Manificat L"
Background And Aim: The clinical utility of transesophageal echocardiography (TEE) after brain ischemia (BI) remains a matter of debate. We aimed to evaluate the clinical impact of TEE and to build a score that could help physicians to identify which patients should better benefit from TEE.
Methods: This prospective, multicenter, observational study included patients over 18 years old, hospitalized for BI.
Background: The presence of pre-infarction angina (PIA) has been shown to confer cardioprotection after ST-segment elevation myocardial infarction (STEMI). However, the clinical impact of PIA in non-ST-segment elevation myocardial infarction (NSTEMI) remains to be determined.
Methods And Results: From the obseRvatoire des Infarctus de Côte d'Or (RICO) survey, 1541 consecutive patients admitted in intensive care unit with a first NSTEMI were included.
Background: An elevated body mass index (BMI) has been reported to be associated with a lower rate of death after acute myocardial infarction (AMI). However, waist circumference (WC) may be a better marker of cardiovascular risk than BMI. We used data from a contemporary French population-based cohort of patients with AMI to analyze the impact of WC and BMI on death rates.
View Article and Find Full Text PDFBackground: Randomized studies have shown a reduction in cardiovascular events associated with low doses of statin among hypertensive patients at only moderate cardiovascular risk. The hypothesis of the present study was that statin therapy initiated during hospitalization could improve the long-term outcome after acute myocardial infarction (MI) in hypertensive patients.
Methods: From the French regional obserRvatoire des Infarctus de Côte d'Or (RICO) survey, 1076 patients with a history of hypertension, surviving acute MI were included.
Objective: The prognosis of patients with acute myocardial infarction (MI), according to the new criteria for impaired fasting glucose (IFG) (FG 100-126 mg/dl), has not been evaluated.
Research Design And Methods: A total of 2353 patients with acute MI and surviving at d 5 after admission were analyzed for short-term morbidity and mortality. FG was obtained at d 4 and 5.
Objective: To determine the prevalence of chronic oral anticoagulant drug treatment (COA) among patients with acute myocardial infarction (AMI) and its impact on management and outcome.
Methods: All patients with ST segment elevation AMI on the RICO (a French regional survey for AMI) database were included in this analysis. COA was defined as continuous use >or= 48 hours before AMI.
The aims of this study were to evaluate new tools of risk stratification in an unselected population of myocardial infarction (MI), usable in a pre-hospital situation, and to compare the risk profile of these patients with those of other clinical trials or myocardial infarction registries. The risk scores of death at 30 days (TIMI score and TIMI risk index) based on data available in the context of coronary emergencies, were applied to the population base of the MI observatory of myocardial infarction in the Côte d'Or (RICO). The risk profile was expressed by the smoothed graph of frequency distribution of each score.
View Article and Find Full Text PDFBackground: Acute myocardial infarction (AMI) in elderly patients is often unrecognized and associated with poor prognosis.
Objectives: To investigate management and efficacy of reperfusion therapy to the elderly patients with AMI.
Methods: From the January 1, 2001 to October 31, 2002, 964 patients with AMI were included in the French regional RICO survey.
Article Synopsis
- The study examined the prevalence and impact of metabolic syndrome on patients who experienced acute myocardial infarction (AMI), finding that nearly half (46%) of the 633 patients met the criteria for metabolic syndrome.
- Patients with metabolic syndrome were generally older, more likely to be women, and showed higher in-hospital mortality and severe heart failure rates compared to those without the syndrome.
- Hyperglycemia was identified as the strongest predictor of severe heart failure among the components of metabolic syndrome, highlighting its significance in patient outcomes after AMI.
Article Synopsis
- A study examined how plasma N-terminal pro-brain natriuretic peptide (Nt-pro-BNP) levels are linked to short-term outcomes in diabetic patients after a myocardial infarction (MI).
- The results showed significantly higher Nt-pro-BNP levels in diabetic patients compared to non-diabetic patients, which remained significant even after accounting for various health factors.
- High Nt-pro-BNP levels were associated with increased hospital mortality and cardiogenic shock in diabetic patients, highlighting its potential as an important marker for assessing risk after MI.
Objectives: We investigated the impact of an emergency medical services call on the management of acute myocardial infarction, considering time intervals for intervention and revascularization procedures.
Methods: Data were prospectively collected from January 2001 to October 2002 from 531 patients hospitalized for myocardial infarction with ST segment elevation and a pre-hospital delay of less than 24 h.
Results: Only 26% of patients called the emergency medical services at the onset of symptoms (n=140).
[Non-revascularisation of acute coronary syndrome with ST elevation].
Arch Mal Coeur Vaiss
March 2004
National therapeutic strategies in acute coronary syndromes (ACS) required revaluation, especially with regards to reperfusion. RICO is an observatory of ACS in the Côte d'Or district. Between January 1st 2001 and April 31st 2003, the cases of 706 patients with ACS and persistent ST elevation or appearances of left bundle branch block eligible for revascularisation (admitted < 12 hours after onset of symptoms and no contra-indications to thrombolysis), were reviewed.
View Article and Find Full Text PDFMethods And Results: 101 patients hospitalized for acute non-ST-elevation myocardial infarction (NSTEMI) were included in the study. Median N-terminal fragment of the brain natriuretic peptide (BNP) prohormone (Nt-proBNP) plasma level was 136 (40-335) pmol/l. Patients with increasing levels of troponin I [from low (0.
View Article and Find Full Text PDFObjectives: In-hospital outcome after acute myocardial infarction (MI) has not yet been evaluated with regard to the new category of Impaired Fasting Glucose level (IFG) patients defined by the American Diabetes Association (ADA).
Methods: Nine hundred and ninety-nine patients with acute MI from the RICO survey were included in the study. Fasting blood glucose was measured after admission.
Several risk stratification scores for myocardial infarction have been developed in recent years, based on clinical trials. The object of this study was to assess the application of these scores in an unselected population of myocardial in farction in a French department. One thousand and fifty-four patients with acute myocardial infarction were included in the RICO observatory in the Côte d'Or.
View Article and Find Full Text PDFWe report the case of an 85-year-old man with perfectly controlled hypertension and coronary insufficiency who presented with typical giant cell arteritis (GCA). Thirty-six hours after initiation of prednisolone therapy (1 mg/kg/d), acute coronary insufficiency with non-transmural infarction occurred. Outcome was favorable despite disturbances in heart rhythm.
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