Publications by authors named "Janie Wierzbicki"
Org Process Res Dev
August 2024
Article Synopsis
- - Two methods are described for synthesizing ()-(+)-1,2-epoxy-5-hexene using cheap and accessible materials.
- - The first method involves a two-step process with mCPBA epoxidation and chiral resolution, yielding 24-30%.
- - The second method starts with ()-epichlorohydrin, achieving 55-60% yield and high purity through ring-opening and closure reactions. Both methods have been tested successfully on scales of 100-200 grams.
