Publications by authors named "Janie L Astephen"

Radiostereometric analysis is a highly accurate technique that can be used for measuring micromotion at the bone-implant interface. The purpose of this study was to compare the inducible displacement of the uncemented Trabecular Metal (TM; Zimmer, Warsaw, Ind) tibial monoblock component with that of a cemented implant. Inducible displacement of 14 uncemented TM components and 11 cemented components was measured 24 to 48 months postoperatively.

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Knee osteoarthritis (OA) is a multifactoral, progressive disease process of the musculoskeletal system. Mechanical factors have been implicated in the progression of knee OA, but the role of altered joint mechanics and neuromuscular control strategies in progressive mechanisms of the disease have not been fully explored. Previous biomechanical studies of knee OA have characterized changes in joint kinematics and kinetics with the disease, but it has been difficult to determine if these biomechanical changes are involved in the development of disease, are in response to degenerative changes in the joint, or are compensatory mechanisms in response to these degenerative changes or other related factors as joint pain.

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Mechanical factors have been implicated in the progression of knee osteoarthritis (OA). Understanding how these factors change as the condition progresses would elucidate their role and help in developing interventions that could delay the progress of knee OA. In this cross-sectional study, we identified kinematic and kinetic variables at the hip, knee, and ankle joints that change between three clinically distinct levels of knee OA disease severity: asymptomatic, moderate OA, and severe OA.

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