Publications by authors named "Janice Gloria Shen"

Article Synopsis
  • A 26-year-old woman developed a petechial rash and low platelet count (thrombocytopenia) two weeks after receiving the Moderna COVID-19 vaccine, leading to her being admitted to the emergency room.
  • During her hospital stay, her condition was complicated by elevated liver enzymes (transaminitis), which improved after treatment with intravenous steroids and immunoglobulin.
  • Extensive tests ruled out other possible causes for her symptoms, and although there was no definitive proof, the timing of her vaccination suggested that the vaccine might have triggered her health issues.
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Acquired haemophilia A (AHA) is a rare and possibly fatal autoimmune disorder that is challenging to treat. Although a majority of cases are idiopathic, AHA can also be associated with an underlying malignancy, autoimmune disorder, pregnancy, infection or certain medications. The diagnosis and treatment of AHA require a specialist with both clinical and laboratory expertise.

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Recent studies have shown that BRAF inhibitors, such as vemurafenib, are effective in inducing long periods of remission in relapsed hairy cell leukaemia. Acute pancreatitis is one of the rare complications that is reported with vemurafenib use. As severe pancreatitis can be life threatening, physicians should be vigilant of this side effect and promptly treat patients that develop clinical signs and symptoms while receiving vemurafenib.

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