Publications by authors named "Jang-Ho Han"
Article Synopsis
- Reference genes are essential in gene expression studies for consistency across different tissues, particularly in dogs undergoing radiation therapy for diseases like cancer.
- Radiation therapy can harm healthy tissues and alter gene expression, making it crucial to analyze reference gene expression during skin recovery post-treatment.
- The study identified the most stable reference gene for post-irradiation canine tissues using quantitative real-time PCR and three validation algorithms, concluding that a specific gene was best for normalization regardless of radiation exposure.
The present study investigated the terminal differentiation capacity into adipocytes and subsequent growth inhibition in A549 cancer cells treated with pioglitazone (PGZ), a PPARγ activator. The rate of cell growth in A549 cells was significantly (< .05) inhibited in concentrations above 10 μM PGZ while maintaining less cytotoxic effects in MRC-5 fibroblasts.
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