AP collagen peptides (APCPs) promote hair growth by activating the GSK-3β/β-catenin pathway and improve hair condition.

AP collagen peptides (APCPs) are enzymatically decomposed collagen peptides that contain tri-peptides such as glycine-proline-hydroxyproline. We found that APCPs increased the proliferation of both human dermal papilla cells (hDPCs) and human outer root sheath cells (hORSCs). APCPs also stimulated the secretion of several growth factors, including IGFBP-6, PDGF-AB, PIGF and VEGF in hDPCs.

Age-related changes in scalp biophysical parameters: A comparative analysis of the 20s and 50s age groups.

Background: Age-related changes in scalp parameters affect hair quality and scalp condition. However, detailed data on biophysical parameters of the scalp across age groups remain scarce. We aimed to investigate the differences in scalp parameters between individuals in their 20s and 50s and analyze their sex-specific variations.

Identification of skin aging biomarkers correlated with the biomechanical properties.

Background: Skin aging can be described as a combination of intrinsic and extrinsic aging. Various parameters for evaluating skin characteristics have been proposed. However, an accurate biomarker for skin aging and the relationship between biomarkers and biomechanical parameters of the skin is yet to be explored.

Reliability and validity of Korean version of modified: Yale preoperative anxiety scale.

Purpose: The modified Yale Preoperative Anxiety Scale (mYPAS) was developed for evaluating the level of preoperative anxiety in children. The purpose of this study was to develop a Korean version of the mYPAS (K-mYPAS) and to establish its validity and reliability based on the Korean preoperative pediatric patients.

Methods: K-mYPAS was made through stringent back-translation procedure.

Improvement in skin wrinkles using a preparation containing human growth factors and hyaluronic acid serum.

Background: Skin aging is accompanied by wrinkle formation. At some sites, such as the periorbital skin, this is a relatively early phenomenon.

Objective: We evaluated the anti-wrinkle effect of a preparation containing human growth factor and hyaluronic acid serum on periorbital wrinkles (crow's feet).

A quantitative evaluation method using processed optical images and analysis of age-dependent changes on nasolabial lines.

Background/purpose: Nasolabial lines (NL) and wrinkles of the face are major features of aging. Wrinkles have been studied widely by morphological methods using 3-dimensional (3D) photographic analysis instrument, but NL were evaluated by visual scoring usually. To evaluate NL quantitatively, another method is needed.

Reduction in facial hyperpigmentation after treatment with a combination of topical niacinamide and tranexamic acid: a randomized, double-blind, vehicle-controlled trial.

Background: Facial hyperpigmentation occurs in multiple conditions. In addition, many Asian women desire a lighter skin color. Thus, there is a need for the development of skin lightening agents, and niacinamide and tranexamic acid (TXA) are promising candidates.

Metals in airborne particulate matter from the first and second industrial complex area of Taejon city, Korea.

To understand the metal distribution characteristics in a rapidly urbanized area, we collected and analyzed particulate matter (PM) samples for the metal concentrations. Using our measurement data for various metal species, we examined both the extent of metal pollution in the study area and the seasonality in their distribution characteristics. Results showed that each metal exhibited their occurrences in diverse concentration ranges over several orders of magnitude such as the mean values ranging from minimum value of 0.