Publications by authors named "Janet Oxford"
The syntheses and pharmacological profiles of some 2-trifluoromethyl-8-methoxyquinoline-5-carboxamides are described. SCH351591 is a potent selective inhibitor of phosphodiesterase type 4 (PDE4).
View Article and Find Full Text PDFThe synthesis and pharmacological profile of a novel series of 2-substituted 8-methoxyquinolines is described. The 2-trifluoromethyl compound was found to be a potent inhibitor of phosphodiesterase type 4 (PDE4).
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- Researchers explored new bicyclic heteroaryl ring structures to replace a specific part of the rolipram chemical structure.
- This investigation led to the identification of 8-methoxyquinoline-5-carboxamides.
- These compounds were found to be strong inhibitors of the enzyme phosphodiesterase type 4 (PDE4).
The synthesis and pharmacological profile of a novel series of 7-methoxy-furo[2,3-c]pyridine-4-carboxamides is described. Some of these compounds were found to be potent inhibitors of phosphodiesterase type 4 (PDE4).
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