Publications by authors named "Janet Mwambona"

The early period of the COVID-19 pandemic limited access to HIV services for children and adolescents living with HIV (C/ALHIV). To determine progress in providing care and treatment services, we describe viral load coverage (VLC) and suppression (VLS) (<1000 copies/ mL) rates during the COVID-19 pandemic in 12 United States President's Emergency Plan for AIDS Relief (PEPFAR)-supported countries. Data for children (0-9 years) and adolescents (10-19 years) on VLC and VLS were analyzed for 12 sub-Saharan African (SSA) countries between 2019 (pre-COVID-19) and 2020 (during COVID-19).

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Article Synopsis
  • Children under 5 years, especially those with HIV not on antiretroviral treatment, face significantly higher mortality rates compared to older age groups, despite receiving ART.
  • From October 2020 to September 2022, annual death rates among infants aged <1 year and children aged 1-4 years on ART were 4.9% and 2.5%, respectively, which are notably higher than those for individuals aged 5 and older.
  • Improving access to and quality of HIV health services for young children, in line with WHO recommendations, is essential for addressing the poor health outcomes they currently face.
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Botswana remains one of the countries with high prevalence of HIV infection with a population prevalence rate of 17.6 in 2008. In 2009, the Ministry of Health launched male circumcision as an additional strategy to the already existing HIV preventive efforts.

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Background: Male circumcision can reduce the risk of heterosexually acquired HIV-1 infection in men. Neonatal male circumcision (NMC) has many potential advantages over circumcision at older ages, but little is known about its feasibility and safety in resource-limited settings.

Methods: We performed a randomized trial in southeastern Botswana of Mogen clamp and Plastibell, 2 commonly used devices for NMC.

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